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Predictive analyses of regulatory sequences with EUGENe.
Nat Comput Sci. 2023 Nov;3(11):946-956. doi: 10.1038/s43588-023-00544-w. Epub 2023 Nov 16.
Nat Comput Sci. 2023.
PMID: 38177592
Free PMC article.
Single-nucleotide variants within heart enhancers increase binding affinity and disrupt heart development.
Jindal GA, Bantle AT, Solvason JJ, Grudzien JL, D'Antonio-Chronowska A, Lim F, Le SH, Song BP, Ragsac MF, Klie A, Larsen RO, Frazer KA, Farley EK.
Jindal GA, et al. Among authors: solvason jj.
Dev Cell. 2023 Nov 6;58(21):2206-2216.e5. doi: 10.1016/j.devcel.2023.09.005. Epub 2023 Oct 16.
Dev Cell. 2023.
PMID: 37848026
Free article.
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Affinity-optimizing enhancer variants disrupt development.
Lim F, Solvason JJ, Ryan GE, Le SH, Jindal GA, Steffen P, Jandu SK, Farley EK.
Lim F, et al. Among authors: solvason jj.
Nature. 2024 Feb;626(7997):151-159. doi: 10.1038/s41586-023-06922-8. Epub 2024 Jan 17.
Nature. 2024.
PMID: 38233525
Free PMC article.
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