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Structural role of K224 in taniborbactam inhibition of NDM-1.
Ono D, Mojica MF, Bethel CR, Ishii Y, Drusin SI, Moreno DM, Vila AJ, Bonomo RA. Ono D, et al. Among authors: vila aj. Antimicrob Agents Chemother. 2024 Feb 7;68(2):e0133223. doi: 10.1128/aac.01332-23. Epub 2024 Jan 4. Antimicrob Agents Chemother. 2024. PMID: 38174924 Free article.
Structural basis of metallo-β-lactamase resistance to taniborbactam.
Drusin SI, Le Terrier C, Poirel L, Bonomo RA, Vila AJ, Moreno DM. Drusin SI, et al. Among authors: vila aj. Antimicrob Agents Chemother. 2024 Feb 7;68(2):e0116823. doi: 10.1128/aac.01168-23. Epub 2023 Dec 8. Antimicrob Agents Chemother. 2024. PMID: 38063400 Free article.
Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-β-lactamases.
Mojica MF, Mahler SG, Bethel CR, Taracila MA, Kosmopoulou M, Papp-Wallace KM, Llarrull LI, Wilson BM, Marshall SH, Wallace CJ, Villegas MV, Harris ME, Vila AJ, Spencer J, Bonomo RA. Mojica MF, et al. Among authors: vila aj. Biochemistry. 2015 May 26;54(20):3183-96. doi: 10.1021/acs.biochem.5b00106. Epub 2015 May 12. Biochemistry. 2015. PMID: 25915520 Free PMC article.
Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase.
González MM, Kosmopoulou M, Mojica MF, Castillo V, Hinchliffe P, Pettinati I, Brem J, Schofield CJ, Mahler G, Bonomo RA, Llarrull LI, Spencer J, Vila AJ. González MM, et al. Among authors: vila aj. ACS Infect Dis. 2015 Nov 13;1(11):544-54. doi: 10.1021/acsinfecdis.5b00046. Epub 2015 Jul 20. ACS Infect Dis. 2015. PMID: 27623409 Free PMC article.
Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?
Marshall S, Hujer AM, Rojas LJ, Papp-Wallace KM, Humphries RM, Spellberg B, Hujer KM, Marshall EK, Rudin SD, Perez F, Wilson BM, Wasserman RB, Chikowski L, Paterson DL, Vila AJ, van Duin D, Kreiswirth BN, Chambers HF, Fowler VG Jr, Jacobs MR, Pulse ME, Weiss WJ, Bonomo RA. Marshall S, et al. Among authors: vila aj. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02243-16. doi: 10.1128/AAC.02243-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28167541 Free PMC article.
145 results