Faraj A - Search Results

1

Subcutaneous Marzeptacog Alfa (Activated) for On-Demand Treatment of Bleeding Events in Subjects With Hemophilia A or B With Inhibitors.

Faraj A, Nyberg J, Blouse GE, Knudsen T, Simonsson USH. Faraj A, et al. Clin Pharmacol Ther. 2024 Mar;115(3):498-505. doi: 10.1002/cpt.3172. Epub 2024 Jan 16. Clin Pharmacol Ther. 2024. PMID: 38173172

2

Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug.

Faraj A, Knudsen T, Desai S, Neuman L, Blouse GE, Simonsson USH. Faraj A, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Dec;11(12):1628-1637. doi: 10.1002/psp4.12872. Epub 2022 Oct 18. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 36191169 Free PMC article.

3

Model-informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy.

Faraj A, van Wijk RC, Neuman L, Desai S, Blouse GE, Knudsen T, Simonsson USH. Faraj A, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Jul;12(7):977-987. doi: 10.1002/psp4.12967. Epub 2023 May 2. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37042339 Free PMC article. Clinical Trial.

4

Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development.

Mockeliunas L, Faraj A, van Wijk RC, Upton CM, van den Hoogen G, Diacon AH, Simonsson USH. Mockeliunas L, et al. Among authors: faraj a. Front Pharmacol. 2023 Apr 13;14:1150243. doi: 10.3389/fphar.2023.1150243. eCollection 2023. Front Pharmacol. 2023. PMID: 37124198 Free PMC article.

5

Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients.

Faraj A, Le Moan N, Gorina E, Blouse GE, Knudsen T, Simonsson USH. Faraj A, et al. Adv Ther. 2023 Sep;40(9):3739-3750. doi: 10.1007/s12325-023-02570-6. Epub 2023 Jun 21. Adv Ther. 2023. PMID: 37341915 Free PMC article.

6

Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients.

Faraj A, Svensson RJ, Diacon AH, Simonsson USH. Faraj A, et al. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e01905-19. doi: 10.1128/AAC.01905-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32122887 Free PMC article. Clinical Trial.

7

A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis.

Clewe O, Faraj A, Hu Y, Coates ARM, Simonsson USH. Clewe O, et al. Among authors: faraj a. J Pharmacokinet Pharmacodyn. 2020 Oct;47(5):421-430. doi: 10.1007/s10928-020-09694-0. Epub 2020 Jun 1. J Pharmacokinet Pharmacodyn. 2020. PMID: 32488575 Free PMC article.

8

Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions.

Faraj A, Clewe O, Svensson RJ, Mukamolova GV, Barer MR, Simonsson USH. Faraj A, et al. Sci Rep. 2020 Sep 23;10(1):15537. doi: 10.1038/s41598-020-72472-y. Sci Rep. 2020. PMID: 32968142 Free PMC article.

9

Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.

De Jager V, Gupte N, Nunes S, Barnes GL, van Wijk RC, Mostert J, Dorman SE, Abulfathi AA, Upton CM, Faraj A, Nuermberger EL, Lamichhane G, Svensson EM, Simonsson USH, Diacon AH, Dooley KE. De Jager V, et al. Among authors: faraj a. Am J Respir Crit Care Med. 2022 May 15;205(10):1228-1235. doi: 10.1164/rccm.202108-1976OC. Am J Respir Crit Care Med. 2022. PMID: 35258443 Free PMC article. Clinical Trial.

10

Cough as Noninvasive Biomarker for Monitoring Tuberculosis Treatment: A Proof-of-Concept Study.

Janssen S, Upton CM, De Jager VR, Faraj A, Pahar M, Miranda IDS, Diacon AH, Simonsson USH, Niesler TR. Janssen S, et al. Among authors: faraj a. Ann Am Thorac Soc. 2023 Dec;20(12):1822-1825. doi: 10.1513/AnnalsATS.202305-456RL. Ann Am Thorac Soc. 2023. PMID: 37751498 No abstract available.

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