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Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.
Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yu Y, et al. Among authors: hastings pj. bioRxiv [Preprint]. 2023 Dec 13:2023.12.13.571550. doi: 10.1101/2023.12.13.571550. bioRxiv. 2023. PMID: 38168242 Free PMC article. Preprint.
Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.
Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yu Y, et al. Among authors: hastings pj. Res Sq [Preprint]. 2024 Jan 5:rs.3.rs-3641411. doi: 10.21203/rs.3.rs-3641411/v1. Res Sq. 2024. PMID: 38260641 Free PMC article. Preprint.
RPA and Rad27 limit templated and inverted insertions at DNA breaks.
Yu Y, Wang X, Fox J, Li Q, Yu Y, Hastings PJ, Chen K, Ira G. Yu Y, et al. Among authors: hastings pj. bioRxiv [Preprint]. 2024 Mar 7:2024.03.07.583931. doi: 10.1101/2024.03.07.583931. bioRxiv. 2024. PMID: 38496432 Free PMC article. Preprint.
Drugging evolution of antibiotic resistance at a regulatory network hub.
Zhai Y, Pribis JP, Dooling SW, Garcia-Villada L, Minnick PJ, Xia J, Liu J, Mei Q, Fitzgerald DM, Herman C, Hastings PJ, Costa-Mattioli M, Rosenberg SM. Zhai Y, et al. Among authors: hastings pj. Sci Adv. 2023 Jun 23;9(25):eadg0188. doi: 10.1126/sciadv.adg0188. Epub 2023 Jun 23. Sci Adv. 2023. PMID: 37352342 Free PMC article.
The multiple de novo copy number variant (MdnCNV) phenomenon presents with peri-zygotic DNA mutational signatures and multilocus pathogenic variation.
Du H, Jolly A, Grochowski CM, Yuan B, Dawood M, Jhangiani SN, Li H, Muzny D, Fatih JM, Coban-Akdemir Z, Carlin ME, Scheuerle AE, Witzl K, Posey JE, Pendleton M, Harrington E, Juul S, Hastings PJ, Bi W, Gibbs RA, Sedlazeck FJ, Lupski JR, Carvalho CMB, Liu P. Du H, et al. Among authors: hastings pj. Genome Med. 2022 Oct 27;14(1):122. doi: 10.1186/s13073-022-01123-w. Genome Med. 2022. PMID: 36303224 Free PMC article.
Chinese scientists and US leadership in the life sciences.
Holtzman SH, Cohen R, Levin JM, Maraganore J; Signatories to the Statement. Holtzman SH, et al. Nat Biotechnol. 2019 Nov;37(11):1261-1263. doi: 10.1038/s41587-019-0285-x. Nat Biotechnol. 2019. PMID: 31582856 No abstract available.
Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response.
Pribis JP, García-Villada L, Zhai Y, Lewin-Epstein O, Wang AZ, Liu J, Xia J, Mei Q, Fitzgerald DM, Bos J, Austin RH, Herman C, Bates D, Hadany L, Hastings PJ, Rosenberg SM. Pribis JP, et al. Among authors: hastings pj. Mol Cell. 2019 May 16;74(4):785-800.e7. doi: 10.1016/j.molcel.2019.02.037. Epub 2019 Apr 1. Mol Cell. 2019. PMID: 30948267 Free PMC article.
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