Kirby J - Search Results

1

Establishing mRNA and microRNA interactions driving disease heterogeneity in amyotrophic lateral sclerosis patient survival.

Waller R, Bury JJ, Appleby-Mallinder C, Wyles M, Loxley G, Babel A, Shekari S, Kazoka M, Wollff H, Al-Chalabi A, Heath PR, Shaw PJ, Kirby J. Waller R, et al. Among authors: kirby j. Brain Commun. 2023 Dec 7;6(1):fcad331. doi: 10.1093/braincomms/fcad331. eCollection 2024. Brain Commun. 2023. PMID: 38162899 Free PMC article.

2

Differential gene expression in a cell culture model of SOD1-related familial motor neurone disease.

Kirby J, Menzies FM, Cookson MR, Bushby K, Shaw PJ. Kirby J, et al. Hum Mol Genet. 2002 Aug 15;11(17):2061-75. doi: 10.1093/hmg/11.17.2061. Hum Mol Genet. 2002. PMID: 12165567

3

Analysis of the cytosolic proteome in a cell culture model of familial amyotrophic lateral sclerosis reveals alterations to the proteasome, antioxidant defenses, and nitric oxide synthetic pathways.

Allen S, Heath PR, Kirby J, Wharton SB, Cookson MR, Menzies FM, Banks RE, Shaw PJ. Allen S, et al. Among authors: kirby j. J Biol Chem. 2003 Feb 21;278(8):6371-83. doi: 10.1074/jbc.M209915200. Epub 2002 Dec 9. J Biol Chem. 2003. PMID: 12475980 Free article.

4

Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.

Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, Barber SC, Loynes CA, Wood-Allum CA, Lunec J, Shaw PJ. Kirby J, et al. Brain. 2005 Jul;128(Pt 7):1686-706. doi: 10.1093/brain/awh503. Epub 2005 May 4. Brain. 2005. PMID: 15872021

5

Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen.

Wood-Allum CA, Barber SC, Kirby J, Heath P, Holden H, Mead R, Higginbottom A, Allen S, Beaujeux T, Alexson SE, Ince PG, Shaw PJ. Wood-Allum CA, et al. Among authors: kirby j. Brain. 2006 Jul;129(Pt 7):1693-709. doi: 10.1093/brain/awl118. Epub 2006 May 15. Brain. 2006. PMID: 16702190

6

Gene expression assays.

Kirby J, Heath PR, Shaw PJ, Hamdy FC. Kirby J, et al. Adv Clin Chem. 2007;44:247-92. doi: 10.1016/s0065-2423(07)44008-2. Adv Clin Chem. 2007. PMID: 17682345 Review.

7

Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS.

Ferraiuolo L, Heath PR, Holden H, Kasher P, Kirby J, Shaw PJ. Ferraiuolo L, et al. Among authors: kirby j. J Neurosci. 2007 Aug 22;27(34):9201-19. doi: 10.1523/JNEUROSCI.1470-07.2007. J Neurosci. 2007. PMID: 17715356 Free PMC article.

8

Transcriptional response of the neuromuscular system to exercise training and potential implications for ALS.

Ferraiuolo L, De Bono JP, Heath PR, Holden H, Kasher P, Channon KM, Kirby J, Shaw PJ. Ferraiuolo L, et al. Among authors: kirby j. J Neurochem. 2009 Jun;109(6):1714-24. doi: 10.1111/j.1471-4159.2009.06080.x. Epub 2009 Apr 1. J Neurochem. 2009. PMID: 19344372 Free article.

9

Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis.

Kirby J, Goodall EF, Smith W, Highley JR, Masanzu R, Hartley JA, Hibberd R, Hollinger HC, Wharton SB, Morrison KE, Ince PG, McDermott CJ, Shaw PJ. Kirby J, et al. Neurogenetics. 2010 May;11(2):217-25. doi: 10.1007/s10048-009-0218-9. Epub 2009 Sep 17. Neurogenetics. 2010. PMID: 19760257 Free article.

10

Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).

Cox LE, Ferraiuolo L, Goodall EF, Heath PR, Higginbottom A, Mortiboys H, Hollinger HC, Hartley JA, Brockington A, Burness CE, Morrison KE, Wharton SB, Grierson AJ, Ince PG, Kirby J, Shaw PJ. Cox LE, et al. Among authors: kirby j. PLoS One. 2010 Mar 24;5(3):e9872. doi: 10.1371/journal.pone.0009872. PLoS One. 2010. PMID: 20352044 Free PMC article.

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