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Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis.
Eur J Med Chem. 2024 Feb 5;265:116038. doi: 10.1016/j.ejmech.2023.116038. Epub 2023 Dec 18.
Eur J Med Chem. 2024.
PMID: 38157597
Free article.
Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores.
Betageri R, Gilmore T, Kuzmich D, Kirrane TM, Bentzien J, Wiedenmayer D, Bekkali Y, Regan J, Berry A, Latli B, Kukulka AJ, Fadra TN, Nelson RM, Goldrick S, Zuvela-Jelaska L, Souza D, Pelletier J, Dinallo R, Panzenbeck M, Torcellini C, Lee H, Pack E, Harcken C, Nabozny G, Thomson DS.
Betageri R, et al. Among authors: wiedenmayer d.
Bioorg Med Chem Lett. 2011 Nov 15;21(22):6842-51. doi: 10.1016/j.bmcl.2011.09.018. Epub 2011 Sep 10.
Bioorg Med Chem Lett. 2011.
PMID: 21963986
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SAR studies of non-zinc-chelating MMP-13 inhibitors: improving selectivity and metabolic stability.
Gao DA, Xiong Z, Heim-Riether A, Amodeo L, August EM, Cao X, Ciccarelli L, Collins BK, Harrington K, Haverty K, Hill-Drzewi M, Li X, Liang S, Margarit SM, Moss N, Nagaraja N, Proudfoot J, Roman R, Schlyer S, Keenan LS, Taylor S, Wellenzohn B, Wiedenmayer D, Li J, Farrow NA.
Gao DA, et al. Among authors: wiedenmayer d.
Bioorg Med Chem Lett. 2010 Sep 1;20(17):5039-43. doi: 10.1016/j.bmcl.2010.07.036. Epub 2010 Jul 15.
Bioorg Med Chem Lett. 2010.
PMID: 20675133
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