Dooley S - Search Results

1

The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation.

Wang S, Link F, Han M, Chaudhary R, Asimakopoulos A, Liebe R, Yao Y, Hammad S, Dropmann A, Krizanac M, Rubie C, Feiner LK, Glanemann M, Ebert MPA, Weiskirchen R, Henis YI, Ehrlich M, Dooley S. Wang S, et al. Among authors: dooley s. Cell Mol Gastroenterol Hepatol. 2024;17(4):567-587. doi: 10.1016/j.jcmgh.2023.12.012. Epub 2023 Dec 27. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38154598 Free PMC article.

2

Cholesterol modulates type I/II TGF-β receptor complexes and alters the balance between Smad and Akt signaling in hepatocytes.

Chaudhary R, Goodman LS, Wang S, Asimakopoulos A, Weiskirchen R, Dooley S, Ehrlich M, Henis YI. Chaudhary R, et al. Among authors: dooley s. Commun Biol. 2024 Jan 2;7(1):8. doi: 10.1038/s42003-023-05654-9. Commun Biol. 2024. PMID: 38168942 Free PMC article.

3

Liver Sinusoidal Endothelial Cells Suppress Bone Morphogenetic Protein 2 Production in Response to TGFβ Pathway Activation.

Colucci S, Altamura S, Marques O, Dropmann A, Horvat NK, Müdder K, Hammad S, Dooley S, Muckenthaler MU. Colucci S, et al. Among authors: dooley s. Hepatology. 2021 Oct;74(4):2186-2200. doi: 10.1002/hep.31900. Epub 2021 Aug 24. Hepatology. 2021. PMID: 33982327

4

Transforming growth factor β latency: A mechanism of cytokine storage and signalling regulation in liver homeostasis and disease.

Li Y, Fan W, Link F, Wang S, Dooley S. Li Y, et al. Among authors: dooley s. JHEP Rep. 2021 Nov 18;4(2):100397. doi: 10.1016/j.jhepr.2021.100397. eCollection 2022 Feb. JHEP Rep. 2021. PMID: 35059619 Free PMC article. Review.

5

A hierarchical regulatory network ensures stable albumin transcription under various pathophysiological conditions.

Feng R, Kan K, Sticht C, Li Y, Wang S, Liu H, Shao C, Munker S, Niess H, Wang S, Meyer C, Liebe R, Ebert MP, Dooley S, Ding H, Weng H. Feng R, et al. Among authors: dooley s. Hepatology. 2022 Dec;76(6):1673-1689. doi: 10.1002/hep.32414. Epub 2022 Mar 7. Hepatology. 2022. PMID: 35257388

6

FOXA2 prevents hyperbilirubinaemia in acute liver failure by maintaining apical MRP2 expression.

Wang S, Feng R, Wang SS, Liu H, Shao C, Li Y, Link F, Munker S, Liebe R, Meyer C, Burgermeister E, Ebert M, Dooley S, Ding H, Weng H. Wang S, et al. Among authors: dooley s. Gut. 2023 Mar;72(3):549-559. doi: 10.1136/gutjnl-2022-326987. Epub 2022 Apr 20. Gut. 2023. PMID: 35444014

7

Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma.

Nwosu ZC, Megger DA, Hammad S, Sitek B, Roessler S, Ebert MP, Meyer C, Dooley S. Nwosu ZC, et al. Among authors: dooley s. Cell Mol Gastroenterol Hepatol. 2017 May 31;4(2):303-323.e1. doi: 10.1016/j.jcmgh.2017.05.004. eCollection 2017 Sep. Cell Mol Gastroenterol Hepatol. 2017. PMID: 28840186 Free PMC article.

8

Systems genetics of hepatocellular damage in vivo and in vitro: identification of a critical network on chromosome 11 in mouse.

Liebe R, Hall RA, Williams RW, Dooley S, Lammert F. Liebe R, et al. Among authors: dooley s. Physiol Genomics. 2013 Oct 16;45(20):931-9. doi: 10.1152/physiolgenomics.00078.2013. Epub 2013 Aug 13. Physiol Genomics. 2013. PMID: 23943854 Free PMC article.

9

Hepatocyte fate upon TGF-β challenge is determined by the matrix environment.

Meyer C, Liebe R, Breitkopf-Heinlein K, Liu Y, Müller A, Rakoczy P, Thomas M, Weng H, Bachmann A, Ebert M, Dooley S. Meyer C, et al. Among authors: dooley s. Differentiation. 2015 Jun;89(5):105-16. doi: 10.1016/j.diff.2015.04.001. Epub 2015 May 14. Differentiation. 2015. PMID: 25982745

10

Roles of TGF-beta in hepatic fibrosis.

Gressner AM, Weiskirchen R, Breitkopf K, Dooley S. Gressner AM, et al. Among authors: dooley s. Front Biosci. 2002 Apr 1;7:d793-807. doi: 10.2741/A812. Front Biosci. 2002. PMID: 11897555 Review.

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