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Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell Pathophysiology.
Sesen J, Ghalali A, Driscoll J, Martinez T, Lupieri A, Zurakowski D, Alexandrescu S, Smith ER, Fehnel KP. Sesen J, et al. Among authors: zurakowski d. Cell Mol Neurobiol. 2023 Dec 27;44(1):12. doi: 10.1007/s10571-023-01447-0. Cell Mol Neurobiol. 2023. PMID: 38150042
Dysregulation of the EphrinB2-EphB4 ratio in pediatric cerebral arteriovenous malformations is associated with endothelial cell dysfunction in vitro and functions as a novel noninvasive biomarker in patients.
Fehnel KP, Penn DL, Duggins-Warf M, Gruber M, Pineda S, Sesen J, Moses-Gardner A, Shah N, Driscoll J, Zurakowski D, Orbach DB, Smith ER. Fehnel KP, et al. Among authors: zurakowski d. Exp Mol Med. 2020 Apr;52(4):658-671. doi: 10.1038/s12276-020-0414-0. Epub 2020 Apr 14. Exp Mol Med. 2020. PMID: 32286515 Free PMC article.
Non-invasive Urinary Biomarkers in Moyamoya Disease.
Sesen J, Driscoll J, Moses-Gardner A, Orbach DB, Zurakowski D, Smith ER. Sesen J, et al. Among authors: zurakowski d. Front Neurol. 2021 Apr 1;12:661952. doi: 10.3389/fneur.2021.661952. eCollection 2021. Front Neurol. 2021. PMID: 33868159 Free PMC article.
Endothelial GNAQ p.R183Q Increases ANGPT2 (Angiopoietin-2) and Drives Formation of Enlarged Blood Vessels.
Huang L, Bichsel C, Norris AL, Thorpe J, Pevsner J, Alexandrescu S, Pinto A, Zurakowski D, Kleiman RJ, Sahin M, Greene AK, Bischoff J. Huang L, et al. Among authors: zurakowski d. Arterioscler Thromb Vasc Biol. 2022 Jan;42(1):e27-e43. doi: 10.1161/ATVBAHA.121.316651. Epub 2021 Oct 21. Arterioscler Thromb Vasc Biol. 2022. PMID: 34670408 Free PMC article.
1,146 results