Hemmings AM - Search Results

1

Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 (StITPK1).

Whitfield HL, Rodriguez RF, Shipton ML, Li AWH, Riley AM, Potter BVL, Hemmings AM, Brearley CA. Whitfield HL, et al. Among authors: hemmings am. Biochemistry. 2024 Jan 2;63(1):42-52. doi: 10.1021/acs.biochem.3c00404. Epub 2023 Dec 26. Biochemistry. 2024. PMID: 38146842 Free PMC article.

2

Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4.

Whitfield HL, He S, Gu Y, Sprigg C, Kuo HF, Chiou TJ, Riley AM, Potter BVL, Hemmings AM, Brearley CA. Whitfield HL, et al. Among authors: hemmings am. Biochem J. 2023 Mar 29;480(6):433-453. doi: 10.1042/BCJ20220579. Biochem J. 2023. PMID: 36896917 Free PMC article.

3

Characterisation of a soil MINPP phytase with remarkable long-term stability and activity from Acinetobacter sp.

Rix GD, Sprigg C, Whitfield H, Hemmings AM, Todd JD, Brearley CA. Rix GD, et al. Among authors: hemmings am. PLoS One. 2022 Aug 31;17(8):e0272015. doi: 10.1371/journal.pone.0272015. eCollection 2022. PLoS One. 2022. PMID: 36044476 Free PMC article.

4

Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.

Acquistapace IM, Thompson EJ, Kühn I, Bedford MR, Brearley CA, Hemmings AM. Acquistapace IM, et al. Among authors: hemmings am. Int J Mol Sci. 2022 Jun 6;23(11):6346. doi: 10.3390/ijms23116346. Int J Mol Sci. 2022. PMID: 35683026 Free PMC article.

5

Structure of a cereal purple acid phytase provides new insights to phytate degradation in plants.

Faba-Rodriguez R, Gu Y, Salmon M, Dionisio G, Brinch-Pedersen H, Brearley CA, Hemmings AM. Faba-Rodriguez R, et al. Among authors: hemmings am. Plant Commun. 2022 Feb 19;3(2):100305. doi: 10.1016/j.xplc.2022.100305. eCollection 2022 Mar 14. Plant Commun. 2022. PMID: 35529950 Free PMC article.

6

Key carboxylate residues for iron transit through the prokaryotic ferritin SynFtn.

Bradley JM, Fair J, Hemmings AM, Le Brun NE. Bradley JM, et al. Among authors: hemmings am. Microbiology (Reading). 2021 Nov;167(11):001105. doi: 10.1099/mic.0.001105. Microbiology (Reading). 2021. PMID: 34825885 Free PMC article.

7

Frontiers in PROTACs.

Hughes GR, Dudey AP, Hemmings AM, Chantry A. Hughes GR, et al. Among authors: hemmings am. Drug Discov Today. 2021 Oct;26(10):2377-2383. doi: 10.1016/j.drudis.2021.04.010. Epub 2021 Apr 17. Drug Discov Today. 2021. PMID: 33872800 Review.

8

Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.

Whitfield H, Hemmings AM, Mills SJ, Baker K, White G, Rushworth S, Riley AM, Potter BVL, Brearley CA. Whitfield H, et al. Among authors: hemmings am. J Med Chem. 2021 Apr 8;64(7):3813-3826. doi: 10.1021/acs.jmedchem.0c01944. Epub 2021 Mar 16. J Med Chem. 2021. PMID: 33724834 Free PMC article.

9

Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism.

Acquistapace IM, Zi Etek MA, Li AWH, Salmon M, Kühn I, Bedford MR, Brearley CA, Hemmings AM. Acquistapace IM, et al. Among authors: hemmings am. J Biol Chem. 2020 Dec 18;295(51):17724-17737. doi: 10.1074/jbc.RA120.015925. J Biol Chem. 2020. PMID: 33454010 Free PMC article.

10

Bacterial iron detoxification at the molecular level.

Bradley JM, Svistunenko DA, Wilson MT, Hemmings AM, Moore GR, Le Brun NE. Bradley JM, et al. Among authors: hemmings am. J Biol Chem. 2020 Dec 18;295(51):17602-17623. doi: 10.1074/jbc.REV120.007746. J Biol Chem. 2020. PMID: 33454001 Free PMC article. Review.

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