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GABAergic and glutamatergic inputs to the medulla oblongata and locus coeruleus noradrenergic pathways are critical for seizures and postictal antinociception neuromodulation.
Mendonça-Dos-Santos M, Gonçalves TCT, Falconi-Sobrinho LL, Dos Anjos-Garcia T, Matias I Jr, de Oliveira RC, Dos Santos Sampaio MF, Dos Santos Cardoso F, Dos Santos WF, Machado HR, Coimbra NC. Mendonça-Dos-Santos M, et al. Among authors: falconi sobrinho ll. Sci Rep. 2024 Feb 19;14(1):4069. doi: 10.1038/s41598-024-53744-3. Sci Rep. 2024. PMID: 38374419 Free PMC article.
Alpha1- and Beta-norepinephrinergic receptors of dorsomedial and ventromedial hypothalamic nuclei modulate panic attack-like defensive behaviour elicited by diencephalic GABAergic neurotransmission disinhibition.
Uribe-Mariño A, Falconi-Sobrinho LL, Castiblanco-Urbina MA, Pigatto GR, Ullah F, da Silva JA, Coimbra NC. Uribe-Mariño A, et al. Among authors: falconi sobrinho ll. Pharmacol Biochem Behav. 2024 Mar;236:173710. doi: 10.1016/j.pbb.2024.173710. Epub 2024 Jan 21. Pharmacol Biochem Behav. 2024. PMID: 38262489
Copaifera langsdorffii Desf. tree oleoresin-induced antinociception recruits µ1- and κ -opioid receptors in the ventrolateral columns of the periaqueductal gray matter.
Santana VC, Marmentini BM, Cruz GG, de Jesus LC, Walicheski L, Beffa FH, Maffei THP, Streg RV, Veiga-Junior VF, Andrighetti CR, Freitas de Lima MC, de Sousa Valladão DM, de Oliveira RC, Neyra MOC, de Araújo Berber RC, Falconi-Sobrinho LL, Coimbra NC, de Oliveira R. Santana VC, et al. Among authors: falconi sobrinho ll. Behav Brain Res. 2024 Mar 12;461:114832. doi: 10.1016/j.bbr.2023.114832. Epub 2023 Dec 23. Behav Brain Res. 2024. PMID: 38142860
Unravelling the dorsal periaqueductal grey matter NMDA receptors relevance in the nitric oxide-mediated panic‑like behaviour and defensive antinociception organised by the anterior hypothalamus of male mice.
Falconi-Sobrinho LL, Dos Anjos-Garcia T, Hernandes PM, Rodrigues BMP, Almada RC, Coimbra NC. Falconi-Sobrinho LL, et al. Psychopharmacology (Berl). 2023 Feb;240(2):319-335. doi: 10.1007/s00213-023-06309-7. Epub 2023 Jan 17. Psychopharmacology (Berl). 2023. PMID: 36648509
Neostriatum neuronal TRPV1-signalling mediates striatal anandamide at high concentration facilitatory influence on neostriato-nigral dishinhibitory GABAergic connections.
da Silva JA, Almada RC, Falconi-Sobrinho LL, Pigatto GR, Hernandes PM, Coimbra NC. da Silva JA, et al. Among authors: falconi sobrinho ll. Brain Res Bull. 2023 Jan;192:128-141. doi: 10.1016/j.brainresbull.2022.11.014. Epub 2022 Nov 19. Brain Res Bull. 2023. PMID: 36414159 Free article.
D2-like receptor activation by intranasal dopamine attenuates fear responses induced by electrical stimulation of the dorsal periaqueductal grey matter, but fails to reduce aversion to pit vipers and T-maze performance.
de Figueiredo RM, Falconi-Sobrinho LL, Leite-Panissi CRA, Huston JP, Mattern C, de Carvalho MC, Coimbra NC. de Figueiredo RM, et al. Among authors: falconi sobrinho ll. J Psychopharmacol. 2022 Nov;36(11):1257-1272. doi: 10.1177/02698811221128018. Epub 2022 Oct 14. J Psychopharmacol. 2022. PMID: 36239034
Panic-like responses of female Wistar rats confronted by Bothrops alternatus pit vipers, or exposure to acute hypoxia: Effect of oestrous cycle.
Ferreira-Sgobbi R, de Figueiredo RM, Frias AT, Matthiesen M, Batistela MF, Falconi-Sobrinho LL, Vilela-Costa HH, Sá SI, Lovick TA, Zangrossi H Jr, Coimbra NC. Ferreira-Sgobbi R, et al. Among authors: falconi sobrinho ll. Eur J Neurosci. 2022 Jan;55(1):32-48. doi: 10.1111/ejn.15548. Epub 2021 Dec 21. Eur J Neurosci. 2022. PMID: 34850475
28 results