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Fenretinide corrects newly found ceramide deficiency in cystic fibrosis.
Guilbault C, De Sanctis JB, Wojewodka G, Saeed Z, Lachance C, Skinner TA, Vilela RM, Kubow S, Lands LC, Hajduch M, Matouk E, Radzioch D. Guilbault C, et al. Among authors: hajduch m. Am J Respir Cell Mol Biol. 2008 Jan;38(1):47-56. doi: 10.1165/rcmb.2007-0036OC. Epub 2007 Jul 26. Am J Respir Cell Mol Biol. 2008. PMID: 17656682
Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy.
Filipcikova R, Oborna I, Brezinova J, Novotny J, Wojewodka G, De Sanctis JB, Radova L, Hajduch M, Radzioch D. Filipcikova R, et al. Among authors: hajduch m. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Mar;159(1):77-82. doi: 10.5507/bp.2013.007. Epub 2013 Feb 25. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015. PMID: 23446211 Free article.
Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.
Ozdian T, Holub D, Maceckova Z, Varanasi L, Rylova G, Rehulka J, Vaclavkova J, Slavik H, Moudry P, Znojek P, Stankova J, de Sanctis JB, Hajduch M, Dzubak P. Ozdian T, et al. Among authors: hajduch m. J Proteomics. 2017 Jun 6;162:73-85. doi: 10.1016/j.jprot.2017.05.005. Epub 2017 May 3. J Proteomics. 2017. PMID: 28478306
Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside.
Garić D, De Sanctis JB, Wojewodka G, Houle D, Cupri S, Abu-Arish A, Hanrahan JW, Hajduch M, Matouk E, Radzioch D. Garić D, et al. Among authors: hajduch m. J Mol Med (Berl). 2017 Oct;95(10):1053-1064. doi: 10.1007/s00109-017-1564-y. Epub 2017 Jul 10. J Mol Med (Berl). 2017. PMID: 28695226 Clinical Trial.
Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction.
Garić D, De Sanctis JB, Dumut DC, Shah J, Peña MJ, Youssef M, Petrof BJ, Kopriva F, Hanrahan JW, Hajduch M, Radzioch D. Garić D, et al. Among authors: hajduch m. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb;1865(2):158538. doi: 10.1016/j.bbalip.2019.158538. Epub 2019 Oct 31. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 31678518
378 results