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Genotoxic therapy and resistance mechanism in gliomas.
Lang F, Liu Y, Chou FJ, Yang C. Lang F, et al. Among authors: yang c. Pharmacol Ther. 2021 Dec;228:107922. doi: 10.1016/j.pharmthera.2021.107922. Epub 2021 Jun 23. Pharmacol Ther. 2021. PMID: 34171339 Free PMC article. Review.
Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via Nrf2.
Liu Y, Chou FJ, Lang F, Zhang M, Song H, Zhang W, Davis DL, Briceno NJ, Zhang Y, Cimino PJ, Zaghloul KA, Gilbert MR, Armstrong TS, Yang C. Liu Y, et al. Among authors: yang c. Clin Cancer Res. 2023 Apr 3;29(7):1305-1316. doi: 10.1158/1078-0432.CCR-22-3179. Clin Cancer Res. 2023. PMID: 36648507 Free PMC article.
IDH mutation and cancer stem cell.
Zhang Y, Liu Y, Lang F, Yang C. Zhang Y, et al. Among authors: yang c. Essays Biochem. 2022 Sep 16;66(4):413-422. doi: 10.1042/EBC20220008. Essays Biochem. 2022. PMID: 35611837
Metabolic reprogramming associated with aggressiveness occurs in the G-CIMP-high molecular subtypes of IDH1mut lower grade gliomas.
Ruiz-Rodado V, Malta TM, Seki T, Lita A, Dowdy T, Celiku O, Cavazos-Saldana A, Li A, Liu Y, Han S, Zhang W, Song H, Davis D, Lee S, Trepel JB, Sabedot TS, Munasinghe J, Yang C, Herold-Mende C, Gilbert MR, Cherukuri MK, Noushmehr H, Larion M. Ruiz-Rodado V, et al. Among authors: yang c. Neuro Oncol. 2020 Apr 15;22(4):480-492. doi: 10.1093/neuonc/noz207. Neuro Oncol. 2020. PMID: 31665443 Free PMC article.
D-2-Hydroxyglutarate in Glioma Biology.
Chou FJ, Liu Y, Lang F, Yang C. Chou FJ, et al. Among authors: yang c. Cells. 2021 Sep 7;10(9):2345. doi: 10.3390/cells10092345. Cells. 2021. PMID: 34571995 Free PMC article. Review.
Combination of PARP inhibitor and temozolomide to suppress chordoma progression.
Cao X, Lu Y, Liu Y, Zhou Y, Song H, Zhang W, Davis D, Cui J, Hao S, Jung J, Wu Q, Park DM, Yang C. Cao X, et al. Among authors: yang c. J Mol Med (Berl). 2019 Aug;97(8):1183-1193. doi: 10.1007/s00109-019-01802-z. Epub 2019 Jun 14. J Mol Med (Berl). 2019. PMID: 31201471 Free PMC article.
Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition.
Ruiz-Rodado V, Lita A, Dowdy T, Celiku O, Saldana AC, Wang H, Yang CZ, Chari R, Li A, Zhang W, Song H, Zhang M, Ahn S, Davis D, Chen X, Zhuang Z, Herold-Mende C, Walters KJ, Gilbert MR, Larion M. Ruiz-Rodado V, et al. Among authors: yang cz. Cancer Metab. 2020 Oct 21;8:23. doi: 10.1186/s40170-020-00229-2. eCollection 2020. Cancer Metab. 2020. PMID: 33101674 Free PMC article.
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