Alessi DR - Search Results

1

Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2.

Zhu H, Tonelli F, Turk M, Prescott A, Alessi DR, Sun J. Zhu H, et al. Among authors: alessi dr. Science. 2023 Dec 22;382(6677):1404-1411. doi: 10.1126/science.adi9926. Epub 2023 Dec 21. Science. 2023. PMID: 38127736 Free PMC article.

2

Essential role of PDK1 in regulating cell size and development in mice.

Lawlor MA, Mora A, Ashby PR, Williams MR, Murray-Tait V, Malone L, Prescott AR, Lucocq JM, Alessi DR. Lawlor MA, et al. Among authors: alessi dr. EMBO J. 2002 Jul 15;21(14):3728-38. doi: 10.1093/emboj/cdf387. EMBO J. 2002. PMID: 12110585 Free PMC article.

3

Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

Kimber WA, Deak M, Prescott AR, Alessi DR. Kimber WA, et al. Among authors: alessi dr. Biochem J. 2003 Dec 1;376(Pt 2):525-35. doi: 10.1042/BJ20031154. Biochem J. 2003. PMID: 14516276 Free PMC article.

4

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR. Boudeau J, et al. Among authors: alessi dr. EMBO J. 2003 Oct 1;22(19):5102-14. doi: 10.1093/emboj/cdg490. EMBO J. 2003. PMID: 14517248 Free PMC article.

5

WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.

Vitari AC, Deak M, Collins BJ, Morrice N, Prescott AR, Phelan A, Humphreys S, Alessi DR. Vitari AC, et al. Among authors: alessi dr. Biochem J. 2004 Feb 15;378(Pt 1):257-68. doi: 10.1042/BJ20031692. Biochem J. 2004. PMID: 14611643 Free PMC article.

6

The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation.

McManus EJ, Collins BJ, Ashby PR, Prescott AR, Murray-Tait V, Armit LJ, Arthur JS, Alessi DR. McManus EJ, et al. Among authors: alessi dr. EMBO J. 2004 May 19;23(10):2071-82. doi: 10.1038/sj.emboj.7600218. Epub 2004 Apr 29. EMBO J. 2004. PMID: 15116068 Free PMC article.

7

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

Komander D, Fairservice A, Deak M, Kular GS, Prescott AR, Peter Downes C, Safrany ST, Alessi DR, van Aalten DM. Komander D, et al. Among authors: alessi dr. EMBO J. 2004 Oct 13;23(20):3918-28. doi: 10.1038/sj.emboj.7600379. Epub 2004 Sep 30. EMBO J. 2004. PMID: 15457207 Free PMC article.

8

Analysis of the LKB1-STRAD-MO25 complex.

Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR. Boudeau J, et al. Among authors: alessi dr. J Cell Sci. 2004 Dec 15;117(Pt 26):6365-75. doi: 10.1242/jcs.01571. Epub 2004 Nov 23. J Cell Sci. 2004. PMID: 15561763

9

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

Al-Hakim AK, Göransson O, Deak M, Toth R, Campbell DG, Morrice NA, Prescott AR, Alessi DR. Al-Hakim AK, et al. Among authors: alessi dr. J Cell Sci. 2005 Dec 1;118(Pt 23):5661-73. doi: 10.1242/jcs.02670. J Cell Sci. 2005. PMID: 16306228

10

Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

Sakamoto K, Zarrinpashneh E, Budas GR, Pouleur AC, Dutta A, Prescott AR, Vanoverschelde JL, Ashworth A, Jovanović A, Alessi DR, Bertrand L. Sakamoto K, et al. Among authors: alessi dr. Am J Physiol Endocrinol Metab. 2006 May;290(5):E780-8. doi: 10.1152/ajpendo.00443.2005. Epub 2005 Dec 6. Am J Physiol Endocrinol Metab. 2006. PMID: 16332922 Free PMC article.

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