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Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids.
Mol Biol Cell. 2024 Mar 1;35(3):ar25. doi: 10.1091/mbc.E23-06-0263. Epub 2023 Dec 20.
Mol Biol Cell. 2024.
PMID: 38117591
Free PMC article.
Fenofibrate increases very-long-chain sphingolipids and improves blood glucose homeostasis in NOD mice.
Holm LJ, Haupt-Jorgensen M, Giacobini JD, Hasselby JP, Bilgin M, Buschard K.
Holm LJ, et al. Among authors: giacobini jd.
Diabetologia. 2019 Dec;62(12):2262-2272. doi: 10.1007/s00125-019-04973-z. Epub 2019 Aug 13.
Diabetologia. 2019.
PMID: 31410530
Free PMC article.
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L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice.
Holm LJ, Haupt-Jorgensen M, Larsen J, Giacobini JD, Bilgin M, Buschard K.
Holm LJ, et al. Among authors: giacobini jd.
PLoS One. 2018 Mar 15;13(3):e0194414. doi: 10.1371/journal.pone.0194414. eCollection 2018.
PLoS One. 2018.
PMID: 29543915
Free PMC article.
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