Gordon D - Search Results

1

Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia.

Nementzik LR, Thumbadoo KM, Murray HC, Gordon D, Yang S, Blair IP, Turner C, Faull RLM, Curtis MA, McLean C, Nicholson GA, Swanson MEV, Scotter EL. Nementzik LR, et al. Among authors: gordon d. Brain Pathol. 2024 May;34(3):e13230. doi: 10.1111/bpa.13230. Epub 2023 Dec 19. Brain Pathol. 2024. PMID: 38115557 Free PMC article.

2

Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.

Gordon D, Dafinca R, Scaber J, Alegre-Abarrategui J, Farrimond L, Scott C, Biggs D, Kent L, Oliver PL, Davies B, Ansorge O, Wade-Martins R, Talbot K. Gordon D, et al. Neurobiol Dis. 2019 Jan;121:148-162. doi: 10.1016/j.nbd.2018.09.024. Epub 2018 Oct 2. Neurobiol Dis. 2019. PMID: 30290270 Free article.

3

Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis.

Chaytow H, Carroll E, Gordon D, Huang YT, van der Hoorn D, Smith HL, Becker T, Becker CG, Faller KME, Talbot K, Gillingwater TH. Chaytow H, et al. Among authors: gordon d. EBioMedicine. 2022 Sep;83:104202. doi: 10.1016/j.ebiom.2022.104202. Epub 2022 Aug 11. EBioMedicine. 2022. PMID: 35963713 Free PMC article.

4

Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice.

Dubinski A, Gagné M, Peyrard S, Gordon D, Talbot K, Vande Velde C. Dubinski A, et al. Among authors: gordon d. Hum Mol Genet. 2023 Jan 6;32(2):319-332. doi: 10.1093/hmg/ddac206. Hum Mol Genet. 2023. PMID: 35994036 Free PMC article.

5

The ALS-associated TDP-43M337V mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner.

Christoforidou E, Moody L, Joilin G, Simoes FA, Gordon D, Talbot K, Hafezparast M. Christoforidou E, et al. Among authors: gordon d. Dis Model Mech. 2024 May 9:dmm.050638. doi: 10.1242/dmm.050638. Online ahead of print. Dis Model Mech. 2024. PMID: 38721655 Free article.

6

Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43.

Christoforidou E, Simoes FA, Gordon D, Talbot K, Hafezparast M. Christoforidou E, et al. Among authors: gordon d. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Jul 27:1-10. doi: 10.1080/21678421.2023.2239276. Online ahead of print. Amyotroph Lateral Scler Frontotemporal Degener. 2023. PMID: 37498094

7

Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.

Williamson MG, Finelli MJ, Sleigh JN, Reddington A, Gordon D, Talbot K, Davies KE, Oliver PL. Williamson MG, et al. Among authors: gordon d. Hum Mol Genet. 2019 Nov 1;28(21):3584-3599. doi: 10.1093/hmg/ddz190. Hum Mol Genet. 2019. PMID: 31642482 Free PMC article.

8

Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.

Sleigh JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K, Schiavo G. Sleigh JN, et al. Among authors: gordon d. Cell Rep. 2020 Mar 17;30(11):3655-3662.e2. doi: 10.1016/j.celrep.2020.02.078. Cell Rep. 2020. PMID: 32187538 Free PMC article.

9

An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.

Feneberg E, Gordon D, Thompson AG, Finelli MJ, Dafinca R, Candalija A, Charles PD, Mäger I, Wood MJ, Fischer R, Kessler BM, Gray E, Turner MR, Talbot K. Feneberg E, et al. Among authors: gordon d. Neurobiol Dis. 2020 Oct;144:105050. doi: 10.1016/j.nbd.2020.105050. Epub 2020 Aug 13. Neurobiol Dis. 2020. PMID: 32800996 Free article.

10

Copper(I)-nitrene platform for chemoproteomic profiling of methionine.

Sahu S, Emenike B, Beusch CM, Bagchi P, Gordon DE, Raj M. Sahu S, et al. Among authors: gordon de. Nat Commun. 2024 May 18;15(1):4243. doi: 10.1038/s41467-024-48403-0. Nat Commun. 2024. PMID: 38762540 Free PMC article.

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