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Persistent ∆FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice.
Stephens GS, Park J, Eagle A, You J, Silva-Pérez M, Fu CH, Choi S, Romain CPS, Sugimoto C, Buffington SA, Zheng Y, Costa-Mattioli M, Liu Y, Robison AJ, Chin J. Stephens GS, et al. Among authors: costa mattioli m. Prog Neurobiol. 2024 Jun;237:102612. doi: 10.1016/j.pneurobio.2024.102612. Epub 2024 Apr 19. Prog Neurobiol. 2024. PMID: 38642602
Precision microbial intervention improves social behavior but not autism severity: A pilot double-blind randomized placebo-controlled trial.
Mazzone L, Dooling SW, Volpe E, Uljarević M, Waters JL, Sabatini A, Arturi L, Abate R, Riccioni A, Siracusano M, Pereira M, Engstrand L, Cristofori F, Adduce D, Francavilla R, Costa-Mattioli M, Hardan AY. Mazzone L, et al. Among authors: costa mattioli m. Cell Host Microbe. 2024 Jan 10;32(1):106-116.e6. doi: 10.1016/j.chom.2023.11.021. Epub 2023 Dec 18. Cell Host Microbe. 2024. PMID: 38113884 Clinical Trial.
Targeted suppression of mTORC2 reduces seizures across models of epilepsy.
Okoh J, Mays J, Bacq A, Oses-Prieto JA, Tyanova S, Chen CJ, Imanbeyev K, Doladilhe M, Zhou H, Jafar-Nejad P, Burlingame A, Noebels J, Baulac S, Costa-Mattioli M. Okoh J, et al. Among authors: costa mattioli m. Nat Commun. 2023 Nov 14;14(1):7364. doi: 10.1038/s41467-023-42922-y. Nat Commun. 2023. PMID: 37963879 Free PMC article.
Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome.
Hooshmandi M, Sharma V, Thörn Perez C, Sood R, Krimbacher K, Wong C, Lister KC, Ureña Guzmán A, Bartley TD, Rocha C, Maussion G, Nadler E, Roque PM, Gantois I, Popic J, Lévesque M, Kaufman RJ, Avoli M, Sanz E, Nader K, Hagerman RJ, Durcan TM, Costa-Mattioli M, Prager-Khoutorsky M, Lacaille JC, Martinez-Cerdeno V, Gibson JR, Huber KM, Sonenberg N, Gkogkas CG, Khoutorsky A. Hooshmandi M, et al. Among authors: costa mattioli m. Neuron. 2023 Oct 4;111(19):3028-3040.e6. doi: 10.1016/j.neuron.2023.06.017. Epub 2023 Jul 19. Neuron. 2023. PMID: 37473758
Drugging evolution of antibiotic resistance at a regulatory network hub.
Zhai Y, Pribis JP, Dooling SW, Garcia-Villada L, Minnick PJ, Xia J, Liu J, Mei Q, Fitzgerald DM, Herman C, Hastings PJ, Costa-Mattioli M, Rosenberg SM. Zhai Y, et al. Among authors: costa mattioli m. Sci Adv. 2023 Jun 23;9(25):eadg0188. doi: 10.1126/sciadv.adg0188. Epub 2023 Jun 23. Sci Adv. 2023. PMID: 37352342 Free PMC article.
Inhibition of Elevated Ras-MAPK Signaling Normalizes Enhanced Motor Learning and Excessive Clustered Dendritic Spine Stabilization in the MECP2-Duplication Syndrome Mouse Model of Autism.
Ash RT, Buffington SA, Park J, Suter B, Costa-Mattioli M, Zoghbi HY, Smirnakis SM. Ash RT, et al. Among authors: costa mattioli m. eNeuro. 2021 Jul 6;8(4):ENEURO.0056-21.2021. doi: 10.1523/ENEURO.0056-21.2021. Print 2021 Jul-Aug. eNeuro. 2021. PMID: 34021030 Free PMC article.
83 results