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Novel approaches in antimalarial drug discovery.
Held J, Kreidenweiss A, Mordmüller B. Held J, et al. Expert Opin Drug Discov. 2013 Nov;8(11):1325-37. doi: 10.1517/17460441.2013.843522. Epub 2013 Oct 3. Expert Opin Drug Discov. 2013. PMID: 24090219 Review.
Antimalarial compounds in Phase II clinical development.
Held J, Jeyaraj S, Kreidenweiss A. Held J, et al. Expert Opin Investig Drugs. 2015 Mar;24(3):363-82. doi: 10.1517/13543784.2015.1000483. Epub 2015 Jan 7. Expert Opin Investig Drugs. 2015. PMID: 25563531 Review.
Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients.
Held J, Supan C, Salazar CLO, Tinto H, Bonkian LN, Nahum A, Sié A, Abdulla S, Cantalloube C, Djeriou E, Bouyou-Akotet M, Ogutu B, Mordmüller B, Kreidenweiss A, Siribie M, Sirima SB, Kremsner PG. Held J, et al. Malar J. 2017 May 4;16(1):188. doi: 10.1186/s12936-017-1832-x. Malar J. 2017. PMID: 28472957 Free PMC article. Clinical Trial.
AQ-13 - an investigational antimalarial drug.
Mengue JB, Held J, Kreidenweiss A. Mengue JB, et al. Among authors: held j. Expert Opin Investig Drugs. 2019 Mar;28(3):217-222. doi: 10.1080/13543784.2019.1560419. Epub 2019 Jan 5. Expert Opin Investig Drugs. 2019. PMID: 30577704 Review.
Monitoring the threatened utility of malaria rapid diagnostic tests by novel high-throughput detection of Plasmodium falciparum hrp2 and hrp3 deletions: A cross-sectional, diagnostic accuracy study.
Kreidenweiss A, Trauner F, Rodi M, Koehne E, Held J, Wyndorps L, Manouana GP, McCall M, Adegnika AA, Lalremruata A, Kremsner PG, Fendel R, Sandri TL. Kreidenweiss A, et al. Among authors: held j. EBioMedicine. 2019 Dec;50:14-22. doi: 10.1016/j.ebiom.2019.10.048. Epub 2019 Nov 21. EBioMedicine. 2019. PMID: 31761619 Free PMC article.
Harmicines - harmine and cinnamic acid hybrids as novel antiplasmodial hits.
Perković I, Raić-Malić S, Fontinha D, Prudêncio M, Pessanha de Carvalho L, Held J, Tandarić T, Vianello R, Zorc B, Rajić Z. Perković I, et al. Among authors: held j. Eur J Med Chem. 2020 Feb 1;187:111927. doi: 10.1016/j.ejmech.2019.111927. Epub 2019 Nov 29. Eur J Med Chem. 2020. PMID: 31812035
624 results