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SINGLE CELL DISSECTION OF DEVELOPMENTAL ORIGINS AND TRANSCRIPTIONAL HETEROGENEITY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA.
Iacobucci I, Zeng AGX, Gao Q, Garcia-Prat L, Baviskar P, Shah S, Murison A, Voisin V, Chan-Seng-Yue M, Cheng C, Qu C, Bailey C, Lear M, Witkowski MT, Zhou X, Peraza AZ, Gangwani K, Advani AS, Luger SM, Litzow MR, Rowe JM, Paietta EM, Stock W, Dick JE, Mullighan CG. Iacobucci I, et al. Among authors: murison a. bioRxiv [Preprint]. 2023 Dec 9:2023.12.04.569954. doi: 10.1101/2023.12.04.569954. bioRxiv. 2023. PMID: 38106088 Free PMC article. Preprint.
Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.
Grillo G, Keshavarzian T, Linder S, Arlidge C, Mout L, Nand A, Teng M, Qamra A, Zhou S, Kron KJ, Murison A, Hawley JR, Fraser M, van der Kwast TH, Raj GV, He HH, Zwart W, Lupien M. Grillo G, et al. Among authors: murison a. Cancer Discov. 2023 Nov 1;13(11):2470-2487. doi: 10.1158/2159-8290.CD-23-0331. Cancer Discov. 2023. PMID: 37694973 Free PMC article.
The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population.
Medina TS, Murison A, Smith M, Kinker GS, Chakravarthy A, Vitiello GAF, Turpin W, Shen SY, Yau HL, Sarmento OF, Faubion W, Lupien M, Silverberg MS, Arrowsmith CH, De Carvalho DD. Medina TS, et al. Among authors: murison a. Front Immunol. 2023 Aug 3;14:1161901. doi: 10.3389/fimmu.2023.1161901. eCollection 2023. Front Immunol. 2023. PMID: 37600767 Free PMC article.
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance.
Fan H, Wang F, Zeng A, Murison A, Tomczak K, Hao D, Jelloul FZ, Wang B, Barrodia P, Liang S, Chen K, Wang L, Zhao Z, Rai K, Jain AK, Dick J, Daver N, Futreal A, Abbas HA. Fan H, et al. Among authors: murison a. Commun Biol. 2023 Jul 21;6(1):765. doi: 10.1038/s42003-023-05120-6. Commun Biol. 2023. PMID: 37479893 Free PMC article.
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L, Booth GT, Geng F, Liu Y, Gomez-Salinero JM, Shieh JH, Redmond D, Xiang JZ, Josefowicz SZ, Trapnell C, Spencer JA, Zangi L, Hadland B, Dick JE, Xie SZ, Rafii S. Itkin T, et al. Among authors: murison a. bioRxiv [Preprint]. 2023 Mar 29:2023.03.27.534417. doi: 10.1101/2023.03.27.534417. bioRxiv. 2023. PMID: 37034724 Free PMC article. Preprint.
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.
Boila LD, Ghosh S, Bandyopadhyay SK, Jin L, Murison A, Zeng AGX, Shaikh W, Bhowmik S, Muddineni SSNA, Biswas M, Sinha S, Chatterjee SS, Mbong N, Gan OI, Bose A, Chakraborty S, Arruda A, Kennedy JA, Mitchell A, Lechman ER, Banerjee D, Milyavsky M, Minden MD, Dick JE, Sengupta A. Boila LD, et al. Among authors: murison a. Leukemia. 2023 Apr;37(4):751-764. doi: 10.1038/s41375-023-01833-z. Epub 2023 Jan 31. Leukemia. 2023. PMID: 36720973
A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.
Boutzen H, Madani Tonekaboni SA, Chan-Seng-Yue M, Murison A, Takayama N, Mbong N, Wagenblast E, Orouji E, Arruda A, Mitchell A, Notta F, Minden MD, Lupien M, Kaufmann KB, Dick JE. Boutzen H, et al. Among authors: murison a. Leukemia. 2022 Nov;36(11):2690-2704. doi: 10.1038/s41375-022-01697-9. Epub 2022 Sep 21. Leukemia. 2022. PMID: 36131042 Free PMC article.
PRMT5 regulates ATF4 transcript splicing and oxidative stress response.
Szewczyk MM, Luciani GM, Vu V, Murison A, Dilworth D, Barghout SH, Lupien M, Arrowsmith CH, Minden MD, Barsyte-Lovejoy D. Szewczyk MM, et al. Among authors: murison a. Redox Biol. 2022 May;51:102282. doi: 10.1016/j.redox.2022.102282. Epub 2022 Mar 11. Redox Biol. 2022. PMID: 35305370 Free PMC article.
Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.
Krivdova G, Voisin V, Schoof EM, Marhon SA, Murison A, McLeod JL, Gabra MM, Zeng AGX, Aigner S, Yee BA, Shishkin AA, Van Nostrand EL, Hermans KG, Trotman-Grant AC, Mbong N, Kennedy JA, Gan OI, Wagenblast E, De Carvalho DD, Salmena L, Minden MD, Bader GD, Yeo GW, Dick JE, Lechman ER. Krivdova G, et al. Among authors: murison a. Cell Rep. 2022 Mar 8;38(10):110481. doi: 10.1016/j.celrep.2022.110481. Cell Rep. 2022. PMID: 35263585 Free article.
41 results