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221 results

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Page 1
Pharmacokinetics (PK) of Tiragolumab in First-in-Human Study in Patients with Mixed Solid Tumors (GO30103).
Garralda E, Oh DY, Italiano A, Bedard PL, Delord JP, Calvo E, LoRusso P, Wainberg Z, Cervantes A, Rodriguez-Vida A, Shemesh CS, Sane R, Mendus D, Ding H, Hendricks R, Meng R, Cho BC, Kim TW, Wu B. Garralda E, et al. Among authors: bedard pl. J Clin Pharmacol. 2024 May;64(5):544-554. doi: 10.1002/jcph.2397. Epub 2024 Jan 17. J Clin Pharmacol. 2024. PMID: 38105505 Clinical Trial.
A Phase I Dose-Escalation Study of LY3405105, a Covalent Inhibitor of Cyclin-Dependent Kinase 7, Administered to Patients With Advanced Solid Tumors.
Garralda E, Schram AM, Bedard PL, Schwartz GK, Yuen E, McNeely SC, Ribeiro S, Cunningham J, Wang Y, Urunuela A, Xu X, LoRusso P. Garralda E, et al. Among authors: bedard pl. Oncologist. 2024 Jan 5;29(1):e131-e140. doi: 10.1093/oncolo/oyad215. Oncologist. 2024. PMID: 37531083 Free PMC article. Clinical Trial.
Correlation Between Surrogate End Points and Overall Survival in a Multi-institutional Clinicogenomic Cohort of Patients With Non-Small Cell Lung or Colorectal Cancer.
Kehl KL, Riely GJ, Lepisto EM, Lavery JA, Warner JL, LeNoue-Newton ML, Sweeney SM, Rudolph JE, Brown S, Yu C, Bedard PL, Schrag D, Panageas KS; American Association of Cancer Research (AACR) Project Genomics Evidence Neoplasia Information Exchange (GENIE) Consortium. Kehl KL, et al. Among authors: bedard pl. JAMA Netw Open. 2021 Jul 1;4(7):e2117547. doi: 10.1001/jamanetworkopen.2021.17547. JAMA Netw Open. 2021. PMID: 34309669 Free PMC article.
Addressing racial and ethnic disparities in AACR project GENIE.
Sweeney SM, Lavery JA, Fuchs HE, Lee JA, Brown S, Panageas KS, Sawyers CL, Bedard PL. Sweeney SM, et al. Among authors: bedard pl. NPJ Precis Oncol. 2023 Aug 31;7(1):81. doi: 10.1038/s41698-023-00425-5. NPJ Precis Oncol. 2023. PMID: 37653066 Free PMC article. No abstract available.
Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors.
Stutheit-Zhao EY, Sanz-Garcia E, Liu ZA, Wong D, Marsh K, Abdul Razak AR, Spreafico A, Bedard PL, Hansen AR, Lheureux S, Torti D, Lam B, Yang SYC, Burgener J, Luo P, Zeng Y, Cheng N, Awadalla P, Bratman SV, Ohashi PS, Pugh TJ, Siu LL. Stutheit-Zhao EY, et al. Among authors: bedard pl. Cancer Discov. 2024 Jun 3;14(6):1048-1063. doi: 10.1158/2159-8290.CD-23-1060. Cancer Discov. 2024. PMID: 38393391 Free PMC article.
Impact on costs and outcomes of multi-gene panel testing for advanced solid malignancies: a cost-consequence analysis using linked administrative data.
Hernando-Calvo A, Nguyen P, Bedard PL, Chan KKW, Saleh RR, Weymann D, Yu C, Amir E, Regier DA, Gyawali B, Kain D, Wilson B, Earle CC, Mittmann N, Abdul Razak AR, Isaranuwatchai W, Sabatini P, Spreafico A, Stockley TL, Pugh TJ, Williams C, Siu LL, Hanna TP. Hernando-Calvo A, et al. Among authors: bedard pl. EClinicalMedicine. 2024 Feb 12;69:102443. doi: 10.1016/j.eclinm.2024.102443. eCollection 2024 Mar. EClinicalMedicine. 2024. PMID: 38380071 Free PMC article.
Genomic Characterization and Clinical Outcomes of Patients with Peritoneal Metastases from the AACR GENIE Biopharma Collaborative Colorectal Cancer Registry.
Sanz-Garcia E, Brown S, Lavery JA, Weiss J, Fuchs HE, Newcomb A, Postle A, Warner JL, LeNoue-Newton ML, Sweeney SM, Pillai S, Yu C, Nichols C, Mastrogiacomo B, Kundra R, Schultz N, Kehl KL, Riely GJ, Schrag D, Govindarajan A, Panageas KS, Bedard PL. Sanz-Garcia E, et al. Among authors: bedard pl. Cancer Res Commun. 2024 Feb 20;4(2):475-486. doi: 10.1158/2767-9764.CRC-23-0409. Cancer Res Commun. 2024. PMID: 38329392 Free PMC article.
Tumor reactive γδ T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient.
Lien SC, Ly D, Yang SYC, Wang BX, Clouthier DL, St Paul M, Gadalla R, Noamani B, Garcia-Batres CR, Boross-Harmer S, Bedard PL, Pugh TJ, Spreafico A, Hirano N, Razak ARA, Ohashi PS. Lien SC, et al. Among authors: bedard pl. Nat Commun. 2024 Feb 6;15(1):1094. doi: 10.1038/s41467-024-45449-y. Nat Commun. 2024. PMID: 38321065 Free PMC article.
221 results