Lai HT - Search Results

1

IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors.

Wu SY, Lai HT, Sanjib Banerjee N, Ma Z, Santana JF, Wei S, Liu X, Zhang M, Zhan J, Chen H, Posner B, Chen Y, Price DH, Chow LT, Zhou J, Chiang CM. Wu SY, et al. Among authors: lai ht. Mol Cell. 2024 Jan 18;84(2):202-220.e15. doi: 10.1016/j.molcel.2023.11.022. Epub 2023 Dec 15. Mol Cell. 2024. PMID: 38103559

2

Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting.

Wu SY, Lee AY, Lai HT, Zhang H, Chiang CM. Wu SY, et al. Among authors: lai ht. Mol Cell. 2013 Mar 7;49(5):843-57. doi: 10.1016/j.molcel.2012.12.006. Epub 2013 Jan 11. Mol Cell. 2013. PMID: 23317504 Free PMC article.

3

Bimolecular Fluorescence Complementation (BiFC) Assay for Direct Visualization of Protein-Protein Interaction in vivo.

Lai HT, Chiang CM. Lai HT, et al. Bio Protoc. 2013;3(20):e935. doi: 10.21769/bioprotoc.935. Epub 2013 Oct 20. Bio Protoc. 2013. PMID: 27390756 Free PMC article.

4

Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration.

Bao L, Chen Y, Lai HT, Wu SY, Wang JE, Hatanpaa KJ, Raisanen JM, Fontenot M, Lega B, Chiang CM, Semenza GL, Wang Y, Luo W. Bao L, et al. Among authors: lai ht. Nucleic Acids Res. 2018 Jul 27;46(13):6576-6591. doi: 10.1093/nar/gky449. Nucleic Acids Res. 2018. PMID: 29860315 Free PMC article.

5

Opposing Functions of BRD4 Isoforms in Breast Cancer.

Wu SY, Lee CF, Lai HT, Yu CT, Lee JE, Zuo H, Tsai SY, Tsai MJ, Ge K, Wan Y, Chiang CM. Wu SY, et al. Among authors: lai ht. Mol Cell. 2020 Jun 18;78(6):1114-1132.e10. doi: 10.1016/j.molcel.2020.04.034. Epub 2020 May 23. Mol Cell. 2020. PMID: 32446320 Free PMC article.

6

Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site.

Liu Z, Li Y, Chen H, Lai HT, Wang P, Wu SY, Wold EA, Leonard PG, Joseph S, Hu H, Chiang CM, Brasier AR, Tian B, Zhou J. Liu Z, et al. Among authors: lai ht. J Med Chem. 2022 Feb 10;65(3):2388-2408. doi: 10.1021/acs.jmedchem.1c01851. Epub 2022 Jan 4. J Med Chem. 2022. PMID: 34982556 Free PMC article.

7

Novel BRD4-p53 Inhibitor SDU-071 Suppresses Proliferation and Migration of MDA-MB-231 Triple-Negative Breast Cancer Cells.

Wang S, Lei K, Lai HT, Liu T, Du L, Wu SY, Ye X, Chiang CM, Li M. Wang S, et al. Among authors: lai ht. ACS Pharmacol Transl Sci. 2024 Mar 12;7(4):1178-1190. doi: 10.1021/acsptsci.4c00057. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633583

8

The impact of COVID-19 and other factors on the usage status of the biologic drug therapies for rheumatoid arthritis: A study from Vietnam.

Bui HB, Lai HT, Nguyen TL, Vu TD, Bui NL, Nguyen VH, Tran TT, Nguyen TP, Nguyen TN, Al-Tawfiq JA, Chu DT. Bui HB, et al. Among authors: lai ht. Reumatol Clin (Engl Ed). 2024 Mar;20(3):128-135. doi: 10.1016/j.reumae.2024.02.003. Reumatol Clin (Engl Ed). 2024. PMID: 38494304 Free article.

9

Comparative Analysis of Swine Antibody Responses following Vaccination with Live-Attenuated and Killed African Swine Fever Virus Vaccines.

Luong HQ, Lai HTL, Truong LQ, Nguyen TN, Vu HD, Nguyen HT, Nguyen LT, Pham TH, McVey DS, Vu HLX. Luong HQ, et al. Among authors: lai htl. Vaccines (Basel). 2023 Nov 3;11(11):1687. doi: 10.3390/vaccines11111687. Vaccines (Basel). 2023. PMID: 38006019 Free PMC article.

10

A Cell-Adapted Live-Attenuated Vaccine Candidate Protects Pigs against the Homologous Strain VNUA-ASFV-05L1, a Representative Strain of the Contemporary Pandemic African Swine Fever Virus.

Truong QL, Wang L, Nguyen TA, Nguyen HT, Tran SD, Vu AT, Le AD, Nguyen VG, Hoang PT, Nguyen YT, Le TL, Van TN, Huynh TML, Lai HTL, Madera R, Li Y, Shi J, Nguyen LT. Truong QL, et al. Among authors: lai htl. Viruses. 2023 Oct 13;15(10):2089. doi: 10.3390/v15102089. Viruses. 2023. PMID: 37896866 Free PMC article.

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