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Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot.
Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Davis RJ, Del Toro DE, Dirain ML, Dram A, Hale LO, Heidarian M, Kim CY, Kucaba TA, Lanz JP, McCray AE, Meszaros S, Miles S, Nelson CR, Rocha IL, Silva EE, Ungaro RF, Walton AH, Xu J, Zeumer-Spataro L, Drewry AM, Liang M, Bible LE, Loftus TJ, Turnbull IR, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EL, et al. Among authors: mazer mb. JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785. JCI Insight. 2024. PMID: 38100268 Free PMC article.
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections.
Remy KE, Mazer M, Striker DA, Ellebedy AH, Walton AH, Unsinger J, Blood TM, Mudd PA, Yi DJ, Mannion DA, Osborne DF, Martin RS, Anand NJ, Bosanquet JP, Blood J, Drewry AM, Caldwell CC, Turnbull IR, Brakenridge SC, Moldwawer LL, Hotchkiss RS. Remy KE, et al. JCI Insight. 2020 Sep 3;5(17):e140329. doi: 10.1172/jci.insight.140329. JCI Insight. 2020. PMID: 32687484 Free PMC article.
Dysregulation of the Leukocyte Signaling Landscape during Acute COVID-19.
Turnbull IR, Fuchs A, Remy KE, Kelly MP, Frazier EP, Ghosh S, Chang SW, Mazer M, Hess A, Leonard J, Hoofnagle M, Colonna M, Hotchkiss RS. Turnbull IR, et al. Res Sq [Preprint]. 2021 Feb 16:rs.3.rs-244150. doi: 10.21203/rs.3.rs-244150/v1. Res Sq. 2021. PMID: 33619472 Free PMC article. Updated. Preprint.
Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research.
Verhoef PA, Kannan S, Sturgill JL, Tucker EW, Morris PE, Miller AC, Sexton TR, Koyner JL, Hejal R, Brakenridge SC, Moldawer LL, Hotchkiss RS, Blood TM, Mazer MB, Bolesta S, Alexander SA, Armaignac DL, Shein SL, Jones C, Hoemann CD, Doctor A, Friess SH, Parker RI, Rotta AT, Remy KE. Verhoef PA, et al. Among authors: mazer mb. Crit Care Explor. 2021 Mar 12;3(3):e0374. doi: 10.1097/CCE.0000000000000374. eCollection 2021 Mar. Crit Care Explor. 2021. PMID: 33786450 Free PMC article. Review.
24 results