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Subcutaneous Administration of Monoclonal Antibodies: Pharmacology, Delivery, Immunogenicity, and Learnings From Applications to Clinical Development.
Davis JD, Bravo Padros M, Conrado DJ, Ganguly S, Guan X, Hassan HE, Hazra A, Irvin SC, Jayachandran P, Kosloski MP, Lin KJ, Mukherjee K, Paccaly A, Papachristos A, Partridge MA, Prabhu S, Visich J, Welf ES, Xu X, Zhao A, Zhu M. Davis JD, et al. Among authors: welf es. Clin Pharmacol Ther. 2024 Mar;115(3):422-439. doi: 10.1002/cpt.3150. Epub 2024 Jan 10. Clin Pharmacol Ther. 2024. PMID: 38093583 Review.
Blebs promote cell survival by assembling oncogenic signalling hubs.
Weems AD, Welf ES, Driscoll MK, Zhou FY, Mazloom-Farsibaf H, Chang BJ, Murali VS, Gihana GM, Weiss BG, Chi J, Rajendran D, Dean KM, Fiolka R, Danuser G. Weems AD, et al. Among authors: welf es. Nature. 2023 Mar;615(7952):517-525. doi: 10.1038/s41586-023-05758-6. Epub 2023 Mar 1. Nature. 2023. PMID: 36859545 Free PMC article.
Real-time multi-angle projection imaging of biological dynamics.
Chang BJ, Manton JD, Sapoznik E, Pohlkamp T, Terrones TS, Welf ES, Murali VS, Roudot P, Hake K, Whitehead L, York AG, Dean KM, Fiolka R. Chang BJ, et al. Among authors: welf es. Nat Methods. 2021 Jul;18(7):829-834. doi: 10.1038/s41592-021-01175-7. Epub 2021 Jun 28. Nat Methods. 2021. PMID: 34183831 Free PMC article.
Actin-Membrane Release Initiates Cell Protrusions.
Welf ES, Miles CE, Huh J, Sapoznik E, Chi J, Driscoll MK, Isogai T, Noh J, Weems AD, Pohlkamp T, Dean K, Fiolka R, Mogilner A, Danuser G. Welf ES, et al. Dev Cell. 2020 Dec 21;55(6):723-736.e8. doi: 10.1016/j.devcel.2020.11.024. Epub 2020 Dec 11. Dev Cell. 2020. PMID: 33308479 Free PMC article.
A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.
Sapoznik E, Chang BJ, Huh J, Ju RJ, Azarova EV, Pohlkamp T, Welf ES, Broadbent D, Carisey AF, Stehbens SJ, Lee KM, Marín A, Hanker AB, Schmidt JC, Arteaga CL, Yang B, Kobayashi Y, Tata PR, Kruithoff R, Doubrovinski K, Shepherd DP, Millett-Sikking A, York AG, Dean KM, Fiolka RP. Sapoznik E, et al. Among authors: welf es. Elife. 2020 Nov 12;9:e57681. doi: 10.7554/eLife.57681. Elife. 2020. PMID: 33179596 Free PMC article.
The nucleus acts as a ruler tailoring cell responses to spatial constraints.
Lomakin AJ, Cattin CJ, Cuvelier D, Alraies Z, Molina M, Nader GPF, Srivastava N, Sáez PJ, Garcia-Arcos JM, Zhitnyak IY, Bhargava A, Driscoll MK, Welf ES, Fiolka R, Petrie RJ, De Silva NS, González-Granado JM, Manel N, Lennon-Duménil AM, Müller DJ, Piel M. Lomakin AJ, et al. Among authors: welf es. Science. 2020 Oct 16;370(6514):eaba2894. doi: 10.1126/science.aba2894. Science. 2020. PMID: 33060332 Free PMC article.
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