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A therapeutic strategy to target distinct sources of IgE and durably reverse allergy.
Limnander A, Kaur N, Asrat S, Tasker C, Boyapati A, Ben LH, Janczy J, Pedraza P, Abreu P, Chen WC, Godin S, Daniel BJ, Chin H, DeVeaux M, Rodriguez Lorenc K, Sirulnik A, Harari O, Stahl N, Sleeman MA, Murphy AJ, Yancopoulos GD, Orengo JM. Limnander A, et al. Among authors: janczy j. Sci Transl Med. 2023 Dec 13;15(726):eadf9561. doi: 10.1126/scitranslmed.adf9561. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091405
Thermal stabilization of diverse biologics using reversible hydrogels.
Marco-Dufort B, Janczy JR, Hu T, Lütolf M, Gatti F, Wolf M, Woods A, Tetter S, Sridhar BV, Tibbitt MW. Marco-Dufort B, et al. Among authors: janczy jr. Sci Adv. 2022 Aug 5;8(31):eabo0502. doi: 10.1126/sciadv.abo0502. Epub 2022 Aug 5. Sci Adv. 2022. PMID: 35930644 Free PMC article.
Thermal Stabilization of Biologics with Photoresponsive Hydrogels.
Sridhar BV, Janczy JR, Hatlevik Ø, Wolfson G, Anseth KS, Tibbitt MW. Sridhar BV, et al. Among authors: janczy jr. Biomacromolecules. 2018 Mar 12;19(3):740-747. doi: 10.1021/acs.biomac.7b01507. Epub 2018 Feb 9. Biomacromolecules. 2018. PMID: 29394044 Free article.
Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.
Ciraci C, Janczy JR, Jain N, Haasken S, Pecli E Silva C, Benjamim CF, Sadler JJ, Olivier AK, Iwakura Y, Shayakhmetov DM, Sutterwala FS, Cassel SL. Ciraci C, et al. Among authors: janczy jr. PLoS One. 2016 Mar 15;11(3):e0151252. doi: 10.1371/journal.pone.0151252. eCollection 2016. PLoS One. 2016. PMID: 26978520 Free PMC article.
Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice.
Cassel SL, Janczy JR, Bing X, Wilson SP, Olivier AK, Otero JE, Iwakura Y, Shayakhmetov DM, Bassuk AG, Abu-Amer Y, Brogden KA, Burns TL, Sutterwala FS, Ferguson PJ. Cassel SL, et al. Among authors: janczy jr. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1072-7. doi: 10.1073/pnas.1318685111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395802 Free PMC article.
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.
Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, Sadler JJ, Knepper-Adrian V, Han R, Qiao L, Eisenbarth SC, Nauseef WM, Cassel SL, Sutterwala FS. Iyer SS, et al. Among authors: janczy jr. Immunity. 2013 Aug 22;39(2):311-323. doi: 10.1016/j.immuni.2013.08.001. Epub 2013 Aug 15. Immunity. 2013. PMID: 23954133 Free PMC article.
Control of innate and adaptive immunity by the inflammasome.
Ciraci C, Janczy JR, Sutterwala FS, Cassel SL. Ciraci C, et al. Among authors: janczy jr. Microbes Infect. 2012 Nov;14(14):1263-70. doi: 10.1016/j.micinf.2012.07.007. Epub 2012 Jul 24. Microbes Infect. 2012. PMID: 22841804 Free PMC article. Review.
Ventilator-induced lung injury is mediated by the NLRP3 inflammasome.
Kuipers MT, Aslami H, Janczy JR, van der Sluijs KF, Vlaar AP, Wolthuis EK, Choi G, Roelofs JJ, Flavell RA, Sutterwala FS, Bresser P, Leemans JC, van der Poll T, Schultz MJ, Wieland CW. Kuipers MT, et al. Among authors: janczy jr. Anesthesiology. 2012 May;116(5):1104-15. doi: 10.1097/ALN.0b013e3182518bc0. Anesthesiology. 2012. PMID: 22531249 Free article.
11 results