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Page 1
ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.
O'Sullivan J, Kothari C, Caron MC, Gagné JP, Jin Z, Nonfoux L, Beneyton A, Coulombe Y, Thomas M, Atalay N, Meng XW, Milano L, Jean D, Boisvert FM, Kaufmann SH, Hendzel MJ, Masson JY, Poirier GG. O'Sullivan J, et al. Among authors: coulombe y. Nucleic Acids Res. 2023 Nov 10;51(20):11056-11079. doi: 10.1093/nar/gkad791. Nucleic Acids Res. 2023. PMID: 37823600 Free PMC article.
FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair.
Pinedo-Carpio E, Dessapt J, Beneyton A, Sacre L, Bérubé MA, Villot R, Lavoie EG, Coulombe Y, Blondeau A, Boulais J, Malina A, Luo VM, Lazaratos AM, Côté JF, Mallette FA, Guarné A, Masson JY, Fradet-Turcotte A, Orthwein A. Pinedo-Carpio E, et al. Among authors: coulombe y. Sci Adv. 2023 Aug 9;9(32):eadf4082. doi: 10.1126/sciadv.adf4082. Epub 2023 Aug 9. Sci Adv. 2023. PMID: 37556550 Free PMC article.
A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene.
Gao Y, Guitton-Sert L, Dessapt J, Coulombe Y, Rodrigue A, Milano L, Blondeau A, Larsen NB, Duxin JP, Hussein S, Fradet-Turcotte A, Masson JY. Gao Y, et al. Among authors: coulombe y. Nat Commun. 2023 Jan 24;14(1):381. doi: 10.1038/s41467-023-35802-y. Nat Commun. 2023. PMID: 36693839 Free PMC article.
ZNF768 links oncogenic RAS to cellular senescence.
Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, Gama-Braga L, Tribouillard L, Gagné A, Duchesne É, Caron D, Bérubé JS, Bérubé JC, Coulombe Y, Orain M, Gélinas Y, Gobeil S, Bossé Y, Masson JY, Elowe S, Bilodeau S, Manem V, Joubert P, Mallette FA, Laplante M. Villot R, et al. Among authors: coulombe y. Nat Commun. 2021 Aug 17;12(1):4841. doi: 10.1038/s41467-021-24932-w. Nat Commun. 2021. PMID: 34404770 Free PMC article.
A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor.
Rodrigue A, Margaillan G, Torres Gomes T, Coulombe Y, Montalban G, da Costa E Silva Carvalho S, Milano L, Ducy M, De-Gregoriis G, Dellaire G, Araújo da Silva W Jr, Monteiro AN, Carvalho MA, Simard J, Masson JY. Rodrigue A, et al. Among authors: coulombe y. Nucleic Acids Res. 2019 Nov 18;47(20):10662-10677. doi: 10.1093/nar/gkz780. Nucleic Acids Res. 2019. PMID: 31586400 Free PMC article.
38 results