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A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity.
Liu C, Zhou D, Dijokaite-Guraliuc A, Supasa P, Duyvesteyn HME, Ginn HM, Selvaraj M, Mentzer AJ, Das R, de Silva TI, Ritter TG, Plowright M, Newman TAH, Stafford L, Kronsteiner B, Temperton N, Lui Y, Fellermeyer M, Goulder P, Klenerman P, Dunachie SJ, Barton MI, Kutuzov MA, Dushek O; OPTIC Consortium; Fry EE, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR. Liu C, et al. Cell Rep Med. 2024 May 21;5(5):101553. doi: 10.1016/j.xcrm.2024.101553. Epub 2024 May 8. Cell Rep Med. 2024. PMID: 38723626 Free PMC article.
A pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration.
Beukenhorst AL, Frallicciardi J, Rice KL, Koldijk MH, Moreira de Mello JC, Klap JM, Hadjichrysanthou C, Koch CM, da Costa KAS, Temperton N, de Jong BA, Vietsch H, Ziere B, Julg B, Koudstaal W, Goudsmit J. Beukenhorst AL, et al. Sci Rep. 2024 Feb 15;14(1):3818. doi: 10.1038/s41598-024-53049-5. Sci Rep. 2024. PMID: 38360813 Free PMC article.
Correlation between pseudotyped virus and authentic virus neutralisation assays, a systematic review and meta-analysis of the literature.
Cantoni D, Wilkie C, Bentley EM, Mayora-Neto M, Wright E, Scott S, Ray S, Castillo-Olivares J, Heeney JL, Mattiuzzo G, Temperton NJ. Cantoni D, et al. Among authors: temperton nj. Front Immunol. 2023 Sep 18;14:1184362. doi: 10.3389/fimmu.2023.1184362. eCollection 2023. Front Immunol. 2023. PMID: 37790941 Free PMC article.
Pseudotyped Viruses for Influenza.
Del Rosario JMM, da Costa KAS, Temperton NJ. Del Rosario JMM, et al. Among authors: temperton nj. Adv Exp Med Biol. 2023;1407:153-173. doi: 10.1007/978-981-99-0113-5_8. Adv Exp Med Biol. 2023. PMID: 36920696
Influenza A (N1-N9) and Influenza B (B/Victoria and B/Yamagata) Neuraminidase Pseudotypes as Tools for Pandemic Preparedness and Improved Influenza Vaccine Design.
da Costa KAS, Del Rosario JMM, Ferrari M, Vishwanath S, Asbach B, Kinsley R, Wagner R, Heeney JL, Carnell GW, Temperton NJ. da Costa KAS, et al. Among authors: temperton nj. Vaccines (Basel). 2022 Sep 14;10(9):1520. doi: 10.3390/vaccines10091520. Vaccines (Basel). 2022. PMID: 36146598 Free PMC article.
50 results