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SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease.
Haltom J, Trovao NS, Guarnieri J, Vincent P, Singh U, Tsoy S, O'Leary CA, Bram Y, Widjaja GA, Cen Z, Meller R, Baylin SB, Moss WN, Nikolau BJ, Enguita FJ, Wallace DC, Beheshti A, Schwartz R, Wurtele ES. Haltom J, et al. Among authors: schwartz r. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298847. doi: 10.1101/2023.11.27.23298847. medRxiv. 2023. PMID: 38076862 Free PMC article. Preprint.
Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.
Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J, Shaiber A, Afshinnekoo E, MacKay M, Bram Y, Chandar V, Geiger H, Craney A, Velu P, Melnick AM, Hajirasouliha I, Beheshti A, Taylor D, Saravia-Butler A, Singh U, Wurtele ES, Schisler J, Fennessey S, Corvelo A, Zody MC, Germer S, Salvatore S, Levy S, Wu S, Tatonetti N, Shapira S, Salvatore M, Loda M, Westblade LF, Cushing M, Rennert H, Kriegel AJ, Elemento O, Imielinski M, Borczuk AC, Meydan C, Schwartz RE, Mason CE. Park J, et al. bioRxiv [Preprint]. 2021 Mar 9:2021.03.08.434433. doi: 10.1101/2021.03.08.434433. bioRxiv. 2021. PMID: 33758858 Free PMC article. Preprint.
Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry.
Kastenhuber ER, Jaimes JA, Johnson JL, Mercadante M, Muecksch F, Weisblum Y, Bram Y, Schwartz RE, Whittaker GR, Cantley LC. Kastenhuber ER, et al. Among authors: schwartz re. bioRxiv [Preprint]. 2021 Jul 30:2021.03.31.437960. doi: 10.1101/2021.03.31.437960. bioRxiv. 2021. PMID: 33821268 Free PMC article. Updated. Preprint.
TARGETED DOWN REGULATION OF CORE MITOCHONDRIAL GENES DURING SARS-COV-2 INFECTION.
Guarnieri JW, Dybas JM, Fazelinia H, Kim MS, Frere J, Zhang Y, Albrecht YS, Murdock DG, Angelin A, Singh LN, Weiss SL, Best SM, Lott MT, Cope H, Zaksas V, Saravia-Butler A, Meydan C, Foox J, Mozsary C, Kidane YH, Priebe W, Emmett MR, Meller R, Singh U, Bram Y, tenOever BR, Heise MT, Moorman NJ, Madden EA, Taft-Benz SA, Anderson EJ, Sanders WA, Dickmander RJ, Baxter VK, Baylin SB, Wurtele ES, Moraes-Vieira PM, Taylor D, Mason CE, Schisler JC, Schwartz RE, Beheshti A, Wallace DC. Guarnieri JW, et al. Among authors: schwartz re. bioRxiv [Preprint]. 2022 Feb 22:2022.02.19.481089. doi: 10.1101/2022.02.19.481089. bioRxiv. 2022. PMID: 35233572 Free PMC article. Preprint.
The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro.
Yaron TM, Heaton BE, Levy TM, Johnson JL, Jordan TX, Cohen BM, Kerelsky A, Lin TY, Liberatore KM, Bulaon DK, Kastenhuber ER, Mercadante MN, Shobana-Ganesh K, He L, Schwartz RE, Chen S, Weinstein H, Elemento O, Piskounova E, Nilsson-Payant BE, Lee G, Trimarco JD, Burke KN, Hamele CE, Chaparian RR, Harding AT, Tata A, Zhu X, Tata PR, Smith CM, Possemato AP, Tkachev SL, Hornbeck PV, Beausoleil SA, Anand SK, Aguet F, Getz G, Davidson AD, Heesom K, Kavanagh-Williamson M, Matthews D, tenOever BR, Cantley LC, Blenis J, Heaton NS. Yaron TM, et al. Among authors: schwartz re. bioRxiv [Preprint]. 2020 Dec 16:2020.08.14.251207. doi: 10.1101/2020.08.14.251207. bioRxiv. 2020. PMID: 32817937 Free PMC article. Preprint.
Author Correction: Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Han Y, et al. Among authors: schwartz re. Nature. 2024 May 29. doi: 10.1038/s41586-024-07593-9. Online ahead of print. Nature. 2024. PMID: 38811742 No abstract available.
Administration of intratumoral GD2-directed interleukin-2 immunocytokine and local radiation therapy to activate immune rejection of spontaneous canine melanoma.
Albertini MR, Zuleger CL, Ranheim EA, Shiyanbola O, Sondel PM, Morris ZS, Eickhoff J, Newton MA, Ong IM, Schwartz RW, Hayim R, Kurzman ID, Turek M, Vail DM. Albertini MR, et al. Among authors: schwartz rw. Melanoma Res. 2024 May 20. doi: 10.1097/CMR.0000000000000975. Online ahead of print. Melanoma Res. 2024. PMID: 38768442
5,377 results