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Use of pyridazinediones for tuneable and reversible covalent cysteine modification applied to peptides, proteins and hydrogels.
Rochet LNC, Bahou C, Wojciechowski JP, Koutsopetras I, Britton P, Spears RJ, Thanasi IA, Shao B, Zhong L, Bučar DK, Aliev AE, Porter MJ, Stevens MM, Baker JR, Chudasama V. Rochet LNC, et al. Among authors: spears rj. Chem Sci. 2023 Nov 1;14(47):13743-13754. doi: 10.1039/d3sc04976k. eCollection 2023 Dec 6. Chem Sci. 2023. PMID: 38075666 Free PMC article.
Hydrogel Cross-Linking via Thiol-Reactive Pyridazinediones.
Bahou C, Spears RJ, Ramírez Rosales AM, Rochet LNC, Barber LJ, Stankevich KS, Miranda JF, Butcher TC, Kerrigan AM, Lazarov VK, Grey W, Chudasama V, Spicer CD. Bahou C, et al. Among authors: spears rj. Biomacromolecules. 2023 Nov 13;24(11):4646-4652. doi: 10.1021/acs.biomac.3c00290. Epub 2023 Oct 4. Biomacromolecules. 2023. PMID: 37792488 Free PMC article.
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