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The Spontaneous Incidence of Neurological Clinical Signs in Preclinical Species Using Cage-side Observations or High-definition Video Monitoring: A Retrospective Analysis.
Int J Toxicol. 2024 Mar-Apr;43(2):123-133. doi: 10.1177/10915818231218984. Epub 2023 Dec 8.
Int J Toxicol. 2024.
PMID: 38063479
Early treatment with an M1 and sigma-1 receptor agonist prevents cognitive decline in a transgenic rat model displaying Alzheimer-like amyloid pathology.
Orciani C, Do Carmo S, Foret MK, Hall H, Bonomo Q, Lavagna A, Huang C, Cuello AC.
Orciani C, et al.
Neurobiol Aging. 2023 Dec;132:220-232. doi: 10.1016/j.neurobiolaging.2023.09.010. Epub 2023 Sep 26.
Neurobiol Aging. 2023.
PMID: 37864952
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Long-term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis.
Orciani C, Hall H, Pentz R, Foret MK, Do Carmo S, Cuello AC.
Orciani C, et al.
J Neurochem. 2022 Oct;163(2):149-167. doi: 10.1111/jnc.15683. Epub 2022 Aug 26.
J Neurochem. 2022.
PMID: 35921478
Free article.
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Early loss of locus coeruleus innervation promotes cognitive and neuropathological changes before amyloid plaque deposition in a transgenic rat model of Alzheimer's disease.
Flores-Aguilar L, Hall H, Orciani C, Foret MK, Kovecses O, Ducatenzeiler A, Cuello AC.
Flores-Aguilar L, et al. Among authors: orciani c.
Neuropathol Appl Neurobiol. 2022 Oct;48(6):e12835. doi: 10.1111/nan.12835. Epub 2022 Jul 25.
Neuropathol Appl Neurobiol. 2022.
PMID: 35822518
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Cognitive and brain cytokine profile of non-demented individuals with cerebral amyloid-beta deposition.
Flores-Aguilar L, Iulita MF, Orciani C, Tanna N, Yang J, Bennett DA, Cuello AC.
Flores-Aguilar L, et al. Among authors: orciani c.
J Neuroinflammation. 2021 Jul 4;18(1):147. doi: 10.1186/s12974-021-02169-0.
J Neuroinflammation. 2021.
PMID: 34218796
Free PMC article.
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Searching for new pharmacological targets for the treatment of Alzheimer's disease in Down syndrome.
Caraci F, Iulita MF, Pentz R, Flores Aguilar L, Orciani C, Barone C, Romano C, Drago F, Cuello AC.
Caraci F, et al. Among authors: orciani c.
Eur J Pharmacol. 2017 Dec 15;817:7-19. doi: 10.1016/j.ejphar.2017.10.004. Epub 2017 Oct 5.
Eur J Pharmacol. 2017.
PMID: 28987272
Review.
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