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A multimodal atlas of hepatocellular carcinoma reveals convergent evolutionary paths and 'bad apple' effect on clinical trajectory.
Chen J, Kaya NA, Zhang Y, Kendarsari RI, Sekar K, Lee Chong S, Seshachalam VP, Ling WH, Jin Phua CZ, Lai H, Yang H, Lu B, Lim JQ, Ma S, Chew SC, Chua KP, Alvarez JJS, Wu L, Ooi L, Chung AY, Cheow PC, Kam JH, Kow AW, Ganpathi IS, Bunchaliew C, Thammasiri J, Koh PS, Ong DB, Lim J, de Villa VH, Dela Cruz RD, Loh TJ, Wan WK, Leow WQ, Yang Y, Liu J, Skanderup AJ, Pang YH, Soon GST, Madhavan K, Lim TK, Bonney G, Goh BKP, Chew V, Dan YY, Toh HC, Foo RS, Tam WL, Zhai W, Chow PK. Chen J, et al. Among authors: chow pk. J Hepatol. 2024 May 21:S0168-8278(24)00352-0. doi: 10.1016/j.jhep.2024.05.017. Online ahead of print. J Hepatol. 2024. PMID: 38782118 Free article.
Real-World Data on the Diagnosis, Treatment, and Management of Hepatocellular Carcinoma in the Asia-Pacific: The INSIGHT Study.
Sim YK, Chong MC, Gandhi M, Pokharkar YM, Zhu Y, Shi L, Lequn L, Chen CH, Kudo M, Lee JH, Strasser SI, Chanwat R, Chow PKH; Asia-Pacific Hepatocellular Carcinoma Trials Group. Sim YK, et al. Among authors: chow pkh. Liver Cancer. 2023 Oct 9;13(3):298-313. doi: 10.1159/000534513. eCollection 2024 Jun. Liver Cancer. 2023. PMID: 38756144 Free PMC article.
Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy.
Li Z, Pai R, Gupta S, Currenti J, Guo W, Di Bartolomeo A, Feng H, Zhang Z, Li Z, Liu L, Singh A, Bai Y, Yang B, Mishra A, Yang K, Qiao L, Wallace M, Yin Y, Xia Q, Chan JKY, George J, Chow PK, Ginhoux F, Sharma A. Li Z, et al. Among authors: chow pk. Nat Cancer. 2024 Jan;5(1):167-186. doi: 10.1038/s43018-023-00672-2. Epub 2024 Jan 2. Nat Cancer. 2024. PMID: 38168935
Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial.
Qin S, Chen M, Cheng AL, Kaseb AO, Kudo M, Lee HC, Yopp AC, Zhou J, Wang L, Wen X, Heo J, Tak WY, Nakamura S, Numata K, Uguen T, Hsiehchen D, Cha E, Hack SP, Lian Q, Ma N, Spahn JH, Wang Y, Wu C, Chow PKH; IMbrave050 investigators. Qin S, et al. Among authors: chow pkh. Lancet. 2023 Nov 18;402(10415):1835-1847. doi: 10.1016/S0140-6736(23)01796-8. Epub 2023 Oct 20. Lancet. 2023. PMID: 37871608 Clinical Trial.
Flying squirrels, hidden treasures.
Chow PKY. Chow PKY. Elife. 2023 Jul 7;12:e89823. doi: 10.7554/eLife.89823. Elife. 2023. PMID: 37417551 Free PMC article.
344 results