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Page 1
Inhibiting stromal Class I HDACs curbs pancreatic cancer progression.
Liang G, Oh TG, Hah N, Tiriac H, Shi Y, Truitt ML, Antal CE, Atkins AR, Li Y, Fraser C, Ng S, Pinto AFM, Nelson DC, Estepa G, Bashi S, Banayo E, Dai Y, Liddle C, Yu RT, Hunter T, Engle DD, Han H, Von Hoff DD, Downes M, Evans RM. Liang G, et al. Among authors: liddle c. Nat Commun. 2023 Dec 6;14(1):7791. doi: 10.1038/s41467-023-42178-6. Nat Commun. 2023. PMID: 38057326 Free PMC article.
Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes.
Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne T, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu R, Downes M, Evans R, Ryden M, Wabitsch M, Reilly S, Huang J, Saltiel A. Xia W, et al. Among authors: liddle c. Res Sq [Preprint]. 2023 Jun 2:rs.3.rs-2923510. doi: 10.21203/rs.3.rs-2923510/v1. Res Sq. 2023. PMID: 37398165 Free PMC article. Updated. Preprint.
Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression.
Fu T, Huan T, Rahman G, Zhi H, Xu Z, Oh TG, Guo J, Coulter S, Tripathi A, Martino C, McCarville JL, Zhu Q, Cayabyab F, Low B, He M, Xing S, Vargas F, Yu RT, Atkins A, Liddle C, Ayres J, Raffatellu M, Dorrestein PC, Downes M, Knight R, Evans RM. Fu T, et al. Among authors: liddle c. Cell Rep. 2023 Aug 29;42(8):112997. doi: 10.1016/j.celrep.2023.112997. Epub 2023 Aug 22. Cell Rep. 2023. PMID: 37611587 Free PMC article.
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer.
Antal CE, Oh TG, Aigner S, Luo EC, Yee BA, Campos T, Tiriac H, Rothamel KL, Cheng Z, Jiao H, Wang A, Hah N, Lenkiewicz E, Lumibao JC, Truitt ML, Estepa G, Banayo E, Bashi S, Esparza E, Munoz RM, Diedrich JK, Sodir NM, Mueller JR, Fraser CR, Borazanci E, Propper D, Von Hoff DD, Liddle C, Yu RT, Atkins AR, Han H, Lowy AM, Barrett MT, Engle DD, Evan GI, Yeo GW, Downes M, Evans RM. Antal CE, et al. Among authors: liddle c. Nat Commun. 2023 Sep 6;14(1):5195. doi: 10.1038/s41467-023-40798-6. Nat Commun. 2023. PMID: 37673892 Free PMC article.
Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation.
Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne TE, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu RT, Downes M, Evans RM, Rydén M, Wabitsch M, Wang Z, Hakozaki H, Schöneberg J, Reilly SM, Huang J, Saltiel AR. Xia W, et al. Among authors: liddle c. Nat Metab. 2024 Feb;6(2):273-289. doi: 10.1038/s42255-024-00978-0. Epub 2024 Jan 29. Nat Metab. 2024. PMID: 38286821 Free PMC article.
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease.
Pan Z, El Sharkway R, Bayoumi A, Metwally M, Gloss BS, Brink R, Lu DB, Liddle C, Alqahtani SA, Yu J, O'Connell PJ, George J, Eslam M. Pan Z, et al. Among authors: liddle c. Sci Transl Med. 2024 Apr 3;16(741):eadj0133. doi: 10.1126/scitranslmed.adj0133. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569018
Cryptococcus neoformans rapidly invades the murine brain by sequential breaching of airway and endothelial tissues barriers, followed by engulfment by microglia.
Francis VI, Liddle C, Camacho E, Kulkarni M, Junior SRS, Harvey JA, Ballou ER, Thomson DD, Brown GD, Hardwick JM, Casadevall A, Witton J, Coelho C. Francis VI, et al. Among authors: liddle c. mBio. 2024 Apr 10;15(4):e0307823. doi: 10.1128/mbio.03078-23. Epub 2024 Mar 21. mBio. 2024. PMID: 38511961 Free PMC article.
241 results