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In Vitro and In Vivo Evaluation of 3D Printed Capsules with Pressure Triggered Release Mechanism for Oral Peptide Delivery.
Berg S, Krause J, Björkbom A, Walter K, Harun S, Granfeldt A, Janzén D, Nunes SF, Antonsson M, Van Zuydam N, Skrtic S, Hugerth A, Weitschies W, Davies N, Abrahamsson B, Bergström CAS. Berg S, et al. Among authors: davies n. J Pharm Sci. 2021 Jan;110(1):228-238. doi: 10.1016/j.xphs.2020.10.066. Epub 2020 Nov 17. J Pharm Sci. 2021. PMID: 33212160
Evaluation in pig of an intestinal administration device for oral peptide delivery.
Berg S, Uggla T, Antonsson M, Nunes SF, Englund M, Rosengren L, Fahraj M, Wu X, Govender R, Söderberg M, Janzén D, Van Zuydam N, Hugerth A, Larsson A, Abrahmsén-Alami S, Abrahamsson B, Davies N, Bergström CAS. Berg S, et al. Among authors: davies n. J Control Release. 2023 Jan;353:792-801. doi: 10.1016/j.jconrel.2022.12.011. Epub 2022 Dec 16. J Control Release. 2023. PMID: 36493948
Injectable Biodegradable Silica Depot for Controlled Subcutaneous Delivery of Antisense Oligonucleotides with beyond Monthly Administration.
McGowan A, Gennemark P, Akieh-Pirkanniemi M, Wirman L, Davies N, Elebring M, Tivesten A, Strimfors M, Hölttä M, Söderberg M, Berntsson V, Balas D, Koskinen M, Leino L, Abrahmsén-Alami S. McGowan A, et al. Among authors: davies n. Mol Pharm. 2024 Jan 1;21(1):143-151. doi: 10.1021/acs.molpharmaceut.3c00663. Epub 2023 Dec 21. Mol Pharm. 2024. PMID: 38126776
An oral antisense oligonucleotide for PCSK9 inhibition.
Gennemark P, Walter K, Clemmensen N, Rekić D, Nilsson CAM, Knöchel J, Hölttä M, Wernevik L, Rosengren B, Kakol-Palm D, Wang Y, Yu RZ, Geary RS, Riney SJ, Monia BP, Isaksson R, Jansson-Löfmark R, Rocha CSJ, Lindén D, Hurt-Camejo E, Crooke R, Tillman L, Rydén-Bergsten T, Carlsson B, Andersson U, Elebring M, Tivesten A, Davies N. Gennemark P, et al. Among authors: davies n. Sci Transl Med. 2021 May 12;13(593):eabe9117. doi: 10.1126/scitranslmed.abe9117. Sci Transl Med. 2021. PMID: 33980578
Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice.
Bartesaghi S, Wallenius K, Hovdal D, Liljeblad M, Wallin S, Dekker N, Barlind L, Davies N, Seeliger F, Winzell MS, Patel S, Theisen M, Brito L, Bergenhem N, Andersson S, Peng XR. Bartesaghi S, et al. Among authors: davies n. Mol Ther Nucleic Acids. 2022 Apr 18;28:500-513. doi: 10.1016/j.omtn.2022.04.010. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35592498 Free PMC article.
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.
Davies N, Hovdal D, Edmunds N, Nordberg P, Dahlén A, Dabkowska A, Arteta MY, Radulescu A, Kjellman T, Höijer A, Seeliger F, Holmedal E, Andihn E, Bergenhem N, Sandinge AS, Johansson C, Hultin L, Johansson M, Lindqvist J, Björsson L, Jing Y, Bartesaghi S, Lindfors L, Andersson S. Davies N, et al. Mol Ther Nucleic Acids. 2021 Mar 13;24:369-384. doi: 10.1016/j.omtn.2021.03.008. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33868782 Free PMC article.
1,943 results