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Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease.
Stem Cell Res Ther. 2023 Dec 5;14(1):345. doi: 10.1186/s13287-023-03592-1.
Stem Cell Res Ther. 2023.
PMID: 38049901
Free PMC article.
Computationally designed hyperactive Cas9 enzymes.
Vos PD, Rossetti G, Mantegna JL, Siira SJ, Gandadireja AP, Bruce M, Raven SA, Khersonsky O, Fleishman SJ, Filipovska A, Rackham O.
Vos PD, et al. Among authors: mantegna jl.
Nat Commun. 2022 May 31;13(1):3023. doi: 10.1038/s41467-022-30598-9.
Nat Commun. 2022.
PMID: 35641498
Free PMC article.
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Mutational rescue of the activity of high-fidelity Cas9 enzymes.
Vos PD, Gandadireja AP, Rossetti G, Siira SJ, Mantegna JL, Filipovska A, Rackham O.
Vos PD, et al. Among authors: mantegna jl.
Cell Rep Methods. 2024 Apr 22;4(4):100756. doi: 10.1016/j.crmeth.2024.100756. Epub 2024 Apr 11.
Cell Rep Methods. 2024.
PMID: 38608689
Free PMC article.
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