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Modeling early treatment response in AML from cell-free tumor DNA.
Wang D, Rausch C, Buerger SA, Tschuri S, Rothenberg-Thurley M, Schulz M, Hasenauer J, Ziemann F, Metzeler KH, Marr C. Wang D, et al. Among authors: rothenberg thurley m. iScience. 2023 Oct 19;26(12):108271. doi: 10.1016/j.isci.2023.108271. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047080 Free PMC article.
Progressive disruption of hematopoietic architecture from clonal hematopoiesis to MDS.
Buck MC, Bast L, Hecker JS, Rivière J, Rothenberg-Thurley M, Vogel L, Wang D, Andrä I, Theis FJ, Bassermann F, Metzeler KH, Oostendorp RAJ, Marr C, Götze KS. Buck MC, et al. Among authors: rothenberg thurley m. iScience. 2023 Jul 10;26(8):107328. doi: 10.1016/j.isci.2023.107328. eCollection 2023 Aug 18. iScience. 2023. PMID: 37520699 Free PMC article.
Double Drop-Off Droplet Digital PCR: A Novel, Versatile Tool for Mutation Screening and Residual Disease Monitoring in Acute Myeloid Leukemia Using Cellular or Cell-Free DNA.
Rausch C, Rothenberg-Thurley M, Buerger SA, Tschuri S, Dufour A, Neusser M, Schneider S, Spiekermann K, Metzeler KH, Ziemann F. Rausch C, et al. J Mol Diagn. 2021 Aug;23(8):975-985. doi: 10.1016/j.jmoldx.2021.05.001. Epub 2021 May 19. J Mol Diagn. 2021. PMID: 34020042 Free article.
Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA.
Konstandin NP, Pastore F, Herold T, Dufour A, Rothenberg-Thurley M, Hinrichsen T, Ksienzyk B, Tschuri S, Schneider S, Hoster E, Berdel WE, Woermann BJ, Sauerland MC, Braess J, Bohlander SK, Klein HG, Hiddemann W, Metzeler KH, Spiekermann K. Konstandin NP, et al. Blood Adv. 2018 Oct 23;2(20):2724-2731. doi: 10.1182/bloodadvances.2018016840. Blood Adv. 2018. PMID: 30337300 Free PMC article.
Acute megakaryoblastic leukaemia shows high frequency of chromosome 1q aberrations and dismal outcome.
Pastore F, Gittinger H, Raab S, Tschuri S, Ksienzyk B, Konstandin NP, Schneider S, Rothenberg-Thurley M, Horny HP, Werner M, Sauerland MC, Amler S, Görlich D, Berdel WE, Wörmann B, Braess J, Hiddemann W, Tischer J, Herold T, Metzeler KH, Spiekermann K. Pastore F, et al. Among authors: rothenberg thurley m. Br J Haematol. 2023 Sep;202(6):1165-1177. doi: 10.1111/bjh.18982. Epub 2023 Jul 16. Br J Haematol. 2023. PMID: 37455345
CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease.
Hecker JS, Hartmann L, Rivière J, Buck MC, van der Garde M, Rothenberg-Thurley M, Fischer L, Winter S, Ksienzyk B, Ziemann F, Solovey M, Rauner M, Tsourdi E, Sockel K, Schneider M, Kubasch AS, Nolde M, Hausmann D, Paulus AC, Lützner J, Roth A, Bassermann F, Spiekermann K, Marr C, Hofbauer LC, Platzbecker U, Metzeler KH, Götze KS. Hecker JS, et al. Blood. 2021 Nov 4;138(18):1727-1732. doi: 10.1182/blood.2020010163. Blood. 2021. PMID: 34139005 Free article.
A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.
Moser C, Jurinovic V, Sagebiel-Kohler S, Ksienzyk B, Batcha AMN, Dufour A, Schneider S, Rothenberg-Thurley M, Sauerland CM, Görlich D, Berdel WE, Krug U, Mansmann U, Hiddemann W, Braess J, Spiekermann K, Greif PA, Vosberg S, Metzeler KH, Kumbrink J, Herold T. Moser C, et al. Blood Adv. 2021 Nov 23;5(22):4752-4761. doi: 10.1182/bloodadvances.2021004814. Blood Adv. 2021. PMID: 34535016 Free PMC article.
Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation.
Kunadt D, Stasik S, Metzeler KH, Röllig C, Schliemann C, Greif PA, Spiekermann K, Rothenberg-Thurley M, Krug U, Braess J, Krämer A, Hochhaus A, Scholl S, Hilgendorf I, Brümmendorf TH, Jost E, Steffen B, Bug G, Einsele H, Görlich D, Sauerland C, Schäfer-Eckart K, Krause SW, Hänel M, Hanoun M, Kaufmann M, Wörmann B, Kramer M, Sockel K, Egger-Heidrich K, Herold T, Ehninger G, Burchert A, Platzbecker U, Berdel WE, Müller-Tidow C, Hiddemann W, Serve H, Stelljes M, Baldus CD, Neubauer A, Schetelig J, Thiede C, Bornhäuser M, Middeke JM, Stölzel F; A. M. L. Cooperative Group (AMLCG), Study Alliance Leukemia (SAL). Kunadt D, et al. J Hematol Oncol. 2022 Sep 5;15(1):126. doi: 10.1186/s13045-022-01339-8. J Hematol Oncol. 2022. PMID: 36064577 Free PMC article.
WT1 and DNMT3A play essential roles in the growth of certain patient AML cells in mice.
Ghalandary M, Gao Y, Amend D, Kutkaite G, Vick B, Spiekermann K, Rothenberg-Thurley M, Metzeler KH, Marcinek A, Subklewe M, Menden MP, Jurinovic V, Bahrami E, Jeremias I. Ghalandary M, et al. Among authors: rothenberg thurley m. Blood. 2023 Feb 23;141(8):955-960. doi: 10.1182/blood.2022016411. Blood. 2023. PMID: 36256915 Free article. No abstract available.
36 results