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A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Wranik M, Kepa MW, Beale EV, James D, Bertrand Q, Weinert T, Furrer A, Glover H, Gashi D, Carrillo M, Kondo Y, Stipp RT, Khusainov G, Nass K, Ozerov D, Cirelli C, Johnson PJM, Dworkowski F, Beale JH, Stubbs S, Zamofing T, Schneider M, Krauskopf K, Gao L, Thorn-Seshold O, Bostedt C, Bacellar C, Steinmetz MO, Milne C, Standfuss J. Wranik M, et al. Among authors: thorn seshold o. Nat Commun. 2023 Dec 2;14(1):7956. doi: 10.1038/s41467-023-43523-5. Nat Commun. 2023. PMID: 38042952 Free PMC article.
Optical Manipulation of F-Actin with Photoswitchable Small Molecules.
Borowiak M, Küllmer F, Gegenfurtner F, Peil S, Nasufovic V, Zahler S, Thorn-Seshold O, Trauner D, Arndt HD. Borowiak M, et al. J Am Chem Soc. 2020 May 20;142(20):9240-9249. doi: 10.1021/jacs.9b12898. Epub 2020 May 11. J Am Chem Soc. 2020. PMID: 32388980 Free PMC article.
Microtubules control cellular shape and coherence in amoeboid migrating cells.
Kopf A, Renkawitz J, Hauschild R, Girkontaite I, Tedford K, Merrin J, Thorn-Seshold O, Trauner D, Häcker H, Fischer KD, Kiermaier E, Sixt M. Kopf A, et al. J Cell Biol. 2020 Jun 1;219(6):e201907154. doi: 10.1083/jcb.201907154. J Cell Biol. 2020. PMID: 32379884 Free PMC article.
BTDAzo: A Photoswitchable TRPC5 Channel Activator.
Müller M, Niemeyer K, Urban N, Ojha NK, Zufall F, Leinders-Zufall T, Schaefer M, Thorn-Seshold O. Müller M, et al. Angew Chem Int Ed Engl. 2022 Sep 5;61(36):e202201565. doi: 10.1002/anie.202201565. Epub 2022 Jul 27. Angew Chem Int Ed Engl. 2022. PMID: 35713469 Free PMC article.
A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton.
Gao L, Meiring JCM, Kraus Y, Wranik M, Weinert T, Pritzl SD, Bingham R, Ntouliou E, Jansen KI, Olieric N, Standfuss J, Kapitein LC, Lohmüller T, Ahlfeld J, Akhmanova A, Steinmetz MO, Thorn-Seshold O. Gao L, et al. Cell Chem Biol. 2021 Feb 18;28(2):228-241.e6. doi: 10.1016/j.chembiol.2020.11.007. Epub 2020 Dec 3. Cell Chem Biol. 2021. PMID: 33275880 Free article.
38 results