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The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells.
Nat Genet. 2024 Jan;56(1):23-26. doi: 10.1038/s41588-023-01602-9. Epub 2023 Nov 30.
Nat Genet. 2024.
PMID: 38036782
Free PMC article.
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage.
Zou X, Koh GCC, Nanda AS, Degasperi A, Urgo K, Roumeliotis TI, Agu CA, Badja C, Momen S, Young J, Amarante TD, Side L, Brice G, Perez-Alonso V, Rueda D, Gomez C, Bushell W, Harris R, Choudhary JS; Genomics England Research Consortium; Jiricny J, Skarnes WC, Nik-Zainal S.
Zou X, et al. Among authors: koh gcc.
Nat Cancer. 2021 Jun;2(6):643-657. doi: 10.1038/s43018-021-00200-0. Epub 2021 Apr 26.
Nat Cancer. 2021.
PMID: 34164627
Free PMC article.
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Substitution mutational signatures in whole-genome-sequenced cancers in the UK population.
Degasperi A, Zou X, Amarante TD, Martinez-Martinez A, Koh GCC, Dias JML, Heskin L, Chmelova L, Rinaldi G, Wang VYW, Nanda AS, Bernstein A, Momen SE, Young J, Perez-Gil D, Memari Y, Badja C, Shooter S, Czarnecki J, Brown MA, Davies HR; Genomics England Research Consortium; Nik-Zainal S.
Degasperi A, et al. Among authors: koh gcc.
Science. 2022 Apr 22;376(6591):science.abl9283. doi: 10.1126/science.abl9283. eCollection 2022 Apr 22.
Science. 2022.
PMID: 35949260
Free PMC article.
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All Driven by Energy Demand? Integrative Comparison of Metabolism of Enterococcus faecalis Wildtype and a Glutamine Synthase Mutant.
Loghmani SB, Zitzow E, Koh GCC, Ulmer A, Veith N, Großeholz R, Rossnagel M, Loesch M, Aebersold R, Kreikemeyer B, Fiedler T, Kummer U.
Loghmani SB, et al. Among authors: koh gcc.
Microbiol Spectr. 2022 Apr 27;10(2):e0240021. doi: 10.1128/spectrum.02400-21. Epub 2022 Mar 2.
Microbiol Spectr. 2022.
PMID: 35234500
Free PMC article.
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