Ahn S - Search Results

1

How carvedilol does not activate β₂-adrenoceptors.

Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. Lefkowitz RJ, et al. Among authors: ahn s. Nat Commun. 2023 Nov 30;14(1):7866. doi: 10.1038/s41467-023-42848-5. Nat Commun. 2023. PMID: 38036531 Free PMC article. No abstract available.

2

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.

Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ. Hara MR, et al. Among authors: ahn s. Nature. 2011 Aug 21;477(7364):349-53. doi: 10.1038/nature10368. Nature. 2011. PMID: 21857681 Free PMC article.

3

β-Arrestin-Biased Allosteric Modulator Potentiates Carvedilol-Stimulated β Adrenergic Receptor Cardioprotection.

Wang J, Pani B, Gokhan I, Xiong X, Kahsai AW, Jiang H, Ahn S, Lefkowitz RJ, Rockman HA. Wang J, et al. Among authors: ahn s. Mol Pharmacol. 2021 Dec;100(6):568-579. doi: 10.1124/molpharm.121.000359. Epub 2021 Sep 24. Mol Pharmacol. 2021. PMID: 34561298 Free PMC article.

4

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor.

Ahn S, Shenoy SK, Wei H, Lefkowitz RJ. Ahn S, et al. J Biol Chem. 2004 Aug 20;279(34):35518-25. doi: 10.1074/jbc.M405878200. Epub 2004 Jun 17. J Biol Chem. 2004. PMID: 15205453 Free article.

5

A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling.

Wisler JW, DeWire SM, Whalen EJ, Violin JD, Drake MT, Ahn S, Shenoy SK, Lefkowitz RJ. Wisler JW, et al. Among authors: ahn s. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16657-62. doi: 10.1073/pnas.0707936104. Epub 2007 Oct 9. Proc Natl Acad Sci U S A. 2007. PMID: 17925438 Free PMC article.

6

Mechanism of intracellular allosteric β₂AR antagonist revealed by X-ray crystal structure.

Liu X, Ahn S, Kahsai AW, Meng KC, Latorraca NR, Pani B, Venkatakrishnan AJ, Masoudi A, Weis WI, Dror RO, Chen X, Lefkowitz RJ, Kobilka BK. Liu X, et al. Among authors: ahn s. Nature. 2017 Aug 24;548(7668):480-484. doi: 10.1038/nature23652. Epub 2017 Aug 16. Nature. 2017. PMID: 28813418 Free PMC article.

7

Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9.

Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, Shenoy SK, Laporte SA, Rockman HA, Lefkowitz RJ. Luttrell LM, et al. Among authors: ahn s. Sci Signal. 2018 Sep 25;11(549):eaat7650. doi: 10.1126/scisignal.aat7650. Sci Signal. 2018. PMID: 30254056 Free PMC article.

8

SnapShot: β-Arrestin Functions.

Ahn S, Shenoy SK, Luttrell LM, Lefkowitz RJ. Ahn S, et al. Cell. 2020 Sep 3;182(5):1362-1362.e1. doi: 10.1016/j.cell.2020.07.034. Cell. 2020. PMID: 32888497 Free article.

9

Unique Positive Cooperativity Between the β-Arrestin-Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor.

Pani B, Ahn S, Rambarat PK, Vege S, Kahsai AW, Liu A, Valan BN, Staus DP, Costa T, Lefkowitz RJ. Pani B, et al. Among authors: ahn s. Mol Pharmacol. 2021 Nov;100(5):513-525. doi: 10.1124/molpharm.121.000363. Epub 2021 Sep 27. Mol Pharmacol. 2021. PMID: 34580163 Free PMC article.

10

[No title available]

[No authors listed] [No authors listed] PMID: 35555965

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