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The epigenomics of schizophrenia, in the mouse.
Javidfar B, Park R, Kassim BS, Bicks LK, Akbarian S. Javidfar B, et al. Am J Med Genet B Neuropsychiatr Genet. 2017 Sep;174(6):631-640. doi: 10.1002/ajmg.b.32566. Epub 2017 Jul 12. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 28699694 Free PMC article. Review.
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling.
Plaza-Jennings AL, Valada A, O'Shea C, Iskhakova M, Hu B, Javidfar B, Ben Hutta G, Lambert TY, Murray J, Kassim B, Chandrasekaran S, Chen BK, Morgello S, Won H, Akbarian S. Plaza-Jennings AL, et al. Among authors: javidfar b. Mol Cell. 2022 Dec 15;82(24):4647-4663.e8. doi: 10.1016/j.molcel.2022.11.016. Mol Cell. 2022. PMID: 36525955 Free PMC article.
Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models.
Rapanelli M, Williams JB, Ma K, Yang F, Zhong P, Patel R, Kumar M, Qin L, Rein B, Wang ZJ, Kassim B, Javidfar B, Couto L, Akbarian S, Yan Z. Rapanelli M, et al. Among authors: javidfar b. Mol Psychiatry. 2022 Aug;27(8):3355-3366. doi: 10.1038/s41380-022-01508-8. Epub 2022 Mar 16. Mol Psychiatry. 2022. PMID: 35296809 Free PMC article.
Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex.
Mitchell AC, Javidfar B, Bicks LK, Neve R, Garbett K, Lander SS, Mirnics K, Morishita H, Wood MA, Jiang Y, Gaisler-Salomon I, Akbarian S. Mitchell AC, et al. Among authors: javidfar b. Nat Commun. 2016 Sep 6;7:12743. doi: 10.1038/ncomms12743. Nat Commun. 2016. PMID: 27597321 Free PMC article.
Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.
Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K. Walsh RM, et al. Among authors: javidfar b. Nat Commun. 2017 May 9;8:15142. doi: 10.1038/ncomms15142. Nat Commun. 2017. PMID: 28485378 Free PMC article.
NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure.
Halene TB, Kozlenkov A, Jiang Y, Mitchell AC, Javidfar B, Dincer A, Park R, Wiseman J, Croxson PL, Giannaris EL, Hof PR, Roussos P, Dracheva S, Hemby SE, Akbarian S. Halene TB, et al. Among authors: javidfar b. Schizophr Res. 2016 Feb;170(2-3):235-44. doi: 10.1016/j.schres.2015.12.016. Epub 2016 Jan 6. Schizophr Res. 2016. PMID: 26776227 Free PMC article.
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
Mitchell AC, Javidfar B, Pothula V, Ibi D, Shen EY, Peter CJ, Bicks LK, Fehr T, Jiang Y, Brennand KJ, Neve RL, Gonzalez-Maeso J, Akbarian S. Mitchell AC, et al. Among authors: javidfar b. Mol Psychiatry. 2018 Jan;23(1):123-132. doi: 10.1038/mp.2016.254. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115742 Free PMC article.
Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19.
Fullard JF, Lee HC, Voloudakis G, Suo S, Javidfar B, Shao Z, Peter C, Zhang W, Jiang S, Corvelo A, Wargnier H, Woodoff-Leith E, Purohit DP, Ahuja S, Tsankova NM, Jette N, Hoffman GE, Akbarian S, Fowkes M, Crary JF, Yuan GC, Roussos P. Fullard JF, et al. Among authors: javidfar b. Genome Med. 2021 Jul 19;13(1):118. doi: 10.1186/s13073-021-00933-8. Genome Med. 2021. PMID: 34281603 Free PMC article.
23 results