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Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos.
McCoy RC, Newnham LJ, Ottolini CS, Hoffmann ER, Chatzimeletiou K, Cornejo OE, Zhan Q, Zaninovic N, Rosenwaks Z, Petrov DA, Demko ZP, Sigurjonsson S, Handyside AH. McCoy RC, et al. Hum Mol Genet. 2018 Jul 15;27(14):2573-2585. doi: 10.1093/hmg/ddy147. Hum Mol Genet. 2018. PMID: 29688390 Free PMC article.
Mathematical modeling of human oocyte aneuploidy.
Tyc KM, McCoy RC, Schindler K, Xing J. Tyc KM, et al. Among authors: mccoy rc. Proc Natl Acad Sci U S A. 2020 May 12;117(19):10455-10464. doi: 10.1073/pnas.1912853117. Epub 2020 Apr 29. Proc Natl Acad Sci U S A. 2020. PMID: 32350135 Free PMC article.
Origins and mechanisms leading to aneuploidy in human eggs.
Wartosch L, Schindler K, Schuh M, Gruhn JR, Hoffmann ER, McCoy RC, Xing J. Wartosch L, et al. Among authors: mccoy rc. Prenat Diagn. 2021 Apr;41(5):620-630. doi: 10.1002/pd.5927. Epub 2021 Mar 22. Prenat Diagn. 2021. PMID: 33860956 Free PMC article.
Let the data do the talking: the need to consider mosaicism during embryo selection.
Viotti M, McCoy RC, Griffin DK, Spinella F, Greco E, Madjunkov M, Madjunkova S, Librach CL, Victor AR, Barnes FL, Zouves CG. Viotti M, et al. Among authors: mccoy rc. Fertil Steril. 2021 Nov;116(5):1212-1219. doi: 10.1016/j.fertnstert.2021.09.008. Epub 2021 Oct 7. Fertil Steril. 2021. PMID: 34627598 Free PMC article. Review.
Haplotype-aware inference of human chromosome abnormalities.
Ariad D, Yan SM, Victor AR, Barnes FL, Zouves CG, Viotti M, McCoy RC. Ariad D, et al. Among authors: mccoy rc. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2109307118. doi: 10.1073/pnas.2109307118. Proc Natl Acad Sci U S A. 2021. PMID: 34772814 Free PMC article.
80 results