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Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity.
Facchini FA, Minotti A, Luraghi A, Romerio A, Gotri N, Matamoros-Recio A, Iannucci A, Palmer C, Wang G, Ingram R, Martin-Santamaria S, Pirianov G, De Andrea M, Valvano MA, Peri F. Facchini FA, et al. Among authors: romerio a. J Med Chem. 2021 Aug 26;64(16):12261-12272. doi: 10.1021/acs.jmedchem.1c00896. Epub 2021 Aug 12. J Med Chem. 2021. PMID: 34382796 Free PMC article.
Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure.
Luraghi A, Ferrandi M, Barassi P, Arici M, Hsu SC, Torre E, Ronchi C, Romerio A, Chang GJ, Ferrari P, Bianchi G, Zaza A, Rocchetti M, Peri F. Luraghi A, et al. Among authors: romerio a. J Med Chem. 2022 May 26;65(10):7324-7333. doi: 10.1021/acs.jmedchem.2c00347. Epub 2022 May 17. J Med Chem. 2022. PMID: 35580334 Free PMC article.
New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants.
Romerio A, Gotri N, Franco AR, Artusa V, Shaik MM, Pasco ST, Atxabal U, Matamoros-Recio A, Mínguez-Toral M, Zalamea JD, Franconetti A, Abrescia NGA, Jimenez-Barbero J, Anguita J, Martín-Santamaría S, Peri F. Romerio A, et al. J Med Chem. 2023 Feb 23;66(4):3010-3029. doi: 10.1021/acs.jmedchem.2c01998. Epub 2023 Feb 2. J Med Chem. 2023. PMID: 36728697 Free PMC article.