Dudler T - Search Results

1

Development and characterization of narsoplimab, a selective MASP-2 inhibitor, for the treatment of lectin-pathway-mediated disorders.

Dudler T, Yaseen S, Cummings WJ. Dudler T, et al. Front Immunol. 2023 Nov 8;14:1297352. doi: 10.3389/fimmu.2023.1297352. eCollection 2023. Front Immunol. 2023. PMID: 38022610 Free PMC article.

2

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.

Ali YM, Lynch NJ, Shaaban AA, Rizk DE, Abdel-Rahman SH, Khatri P, Yabuki M, Yaseen S, Dudler T, Demopulos G, Schwaeble WJ. Ali YM, et al. Among authors: dudler t. Front Immunol. 2023 May 30;14:1192767. doi: 10.3389/fimmu.2023.1192767. eCollection 2023. Front Immunol. 2023. PMID: 37325666 Free PMC article.

3

Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury.

Mercurio D, Pischiutta F, Seminara S, Tribuzio F, Lisi I, Pasetto L, Bonetto V, De Simoni MG, Schwaeble W, Yaseen S, Dudler T, Zanier ER, Fumagalli S. Mercurio D, et al. Among authors: dudler t. J Neuroinflammation. 2024 May 28;21(1):141. doi: 10.1186/s12974-024-03133-4. J Neuroinflammation. 2024. PMID: 38807149 Free PMC article.

4

MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease.

Belcher JD, Nguyen J, Chen C, Abdulla F, Conglin R, Ivy ZK, Cummings J, Dudler T, Vercellotti GM. Belcher JD, et al. Among authors: dudler t. Transl Res. 2022 Nov;249:1-12. doi: 10.1016/j.trsl.2022.06.018. Epub 2022 Jul 22. Transl Res. 2022. PMID: 35878790 Free PMC article.

5

Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy.

Gavriilaki E, Ho VT, Schwaeble W, Dudler T, Daha M, Fujita T, Jodele S. Gavriilaki E, et al. Among authors: dudler t. Exp Hematol Oncol. 2021 Dec 19;10(1):57. doi: 10.1186/s40164-021-00249-8. Exp Hematol Oncol. 2021. PMID: 34924021 Free PMC article. Review.

6

Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.

Ali YM, Ferrari M, Lynch NJ, Yaseen S, Dudler T, Gragerov S, Demopulos G, Heeney JL, Schwaeble WJ. Ali YM, et al. Among authors: dudler t. Front Immunol. 2021 Jul 5;12:714511. doi: 10.3389/fimmu.2021.714511. eCollection 2021. Front Immunol. 2021. PMID: 34290717 Free PMC article.

7

Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury.

Alghadban S, Kenawy HI, Dudler T, Schwaeble WJ, Brunskill NJ. Alghadban S, et al. Among authors: dudler t. Front Immunol. 2019 Sep 23;10:2238. doi: 10.3389/fimmu.2019.02238. eCollection 2019. Front Immunol. 2019. PMID: 31608060 Free PMC article.

8

Cardioprotection by an anti-MASP-2 antibody in a murine model of myocardial infarction.

Clark JE, Dudler T, Marber MS, Schwaeble W. Clark JE, et al. Among authors: dudler t. Open Heart. 2018 Jan 9;5(1):e000652. doi: 10.1136/openhrt-2017-000652. eCollection 2018. Open Heart. 2018. PMID: 29344374 Free PMC article.

9

Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.

Yaseen S, Demopulos G, Dudler T, Yabuki M, Wood CL, Cummings WJ, Tjoelker LW, Fujita T, Sacks S, Garred P, Andrew P, Sim RB, Lachmann PJ, Wallis R, Lynch N, Schwaeble WJ. Yaseen S, et al. Among authors: dudler t. FASEB J. 2017 May;31(5):2210-2219. doi: 10.1096/fj.201601306R. Epub 2017 Feb 10. FASEB J. 2017. PMID: 28188176

10

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.

Orsini F, Chrysanthou E, Dudler T, Cummings WJ, Takahashi M, Fujita T, Demopulos G, De Simoni MG, Schwaeble W. Orsini F, et al. Among authors: dudler t. J Neuroinflammation. 2016 Aug 30;13(1):213. doi: 10.1186/s12974-016-0684-6. J Neuroinflammation. 2016. PMID: 27577570 Free PMC article.

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