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Dynamics of necroptosis in kidney ischemia-reperfusion injury.
Pefanis A, Bongoni AK, McRae JL, Salvaris EJ, Fisicaro N, Murphy JM, Ierino FL, Cowan PJ. Pefanis A, et al. Among authors: murphy jm. Front Immunol. 2023 Nov 2;14:1251452. doi: 10.3389/fimmu.2023.1251452. eCollection 2023. Front Immunol. 2023. PMID: 38022500 Free PMC article.
The anticonvulsive Phenhydan® suppresses extrinsic cell death.
Moerke C, Jaco I, Dewitz C, Müller T, Jacobsen AV, Gautheron J, Fritsch J, Schmitz J, Bräsen JH, Günther C, Murphy JM, Kunzendorf U, Meier P, Krautwald S. Moerke C, et al. Among authors: murphy jm. Cell Death Differ. 2019 Sep;26(9):1631-1645. doi: 10.1038/s41418-018-0232-2. Epub 2018 Nov 15. Cell Death Differ. 2019. PMID: 30442947 Free PMC article.
Regulated necrosis in kidney ischemia-reperfusion injury.
Pefanis A, Ierino FL, Murphy JM, Cowan PJ. Pefanis A, et al. Among authors: murphy jm. Kidney Int. 2019 Aug;96(2):291-301. doi: 10.1016/j.kint.2019.02.009. Epub 2019 Mar 7. Kidney Int. 2019. PMID: 31005270 Free article. Review.
Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS.
Wang T, Perera ND, Chiam MDF, Cuic B, Wanniarachchillage N, Tomas D, Samson AL, Cawthorne W, Valor EN, Murphy JM, Turner BJ. Wang T, et al. Among authors: murphy jm. Cell Death Differ. 2020 May;27(5):1728-1739. doi: 10.1038/s41418-019-0457-8. Epub 2019 Nov 19. Cell Death Differ. 2020. PMID: 31745214 Free PMC article.
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis.
Samson AL, Zhang Y, Geoghegan ND, Gavin XJ, Davies KA, Mlodzianoski MJ, Whitehead LW, Frank D, Garnish SE, Fitzgibbon C, Hempel A, Young SN, Jacobsen AV, Cawthorne W, Petrie EJ, Faux MC, Shield-Artin K, Lalaoui N, Hildebrand JM, Silke J, Rogers KL, Lessene G, Hawkins ED, Murphy JM. Samson AL, et al. Among authors: murphy jm. Nat Commun. 2020 Jun 19;11(1):3151. doi: 10.1038/s41467-020-16887-1. Nat Commun. 2020. PMID: 32561730 Free PMC article.
Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the Pathway.
Pierotti CL, Tanzer MC, Jacobsen AV, Hildebrand JM, Garnier JM, Sharma P, Lucet IS, Cowan AD, Kersten WJA, Luo MX, Liang LY, Fitzgibbon C, Garnish SE, Hempel A, Nachbur U, Huang DCS, Czabotar PE, Silke J, van Delft MF, Murphy JM, Lessene G. Pierotti CL, et al. Among authors: murphy jm. ACS Chem Biol. 2020 Oct 16;15(10):2702-2713. doi: 10.1021/acschembio.0c00482. Epub 2020 Sep 22. ACS Chem Biol. 2020. PMID: 32902249
780 results