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Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor.
Desch M, Wunderlich G, Goettel M, Goetz S, Liesenfeld KH, Chan TS, Rosenbrock H, Sennewald R, Link J, Keller S, Wind S. Desch M, et al. Among authors: goettel m. Eur J Drug Metab Pharmacokinet. 2022 Jan;47(1):91-103. doi: 10.1007/s13318-021-00723-y. Epub 2021 Oct 29. Eur J Drug Metab Pharmacokinet. 2022. PMID: 34716565 Free PMC article. Clinical Trial.
Variation among 532 genomes unveils the origin and evolutionary history of a global insect herbivore.
You M, Ke F, You S, Wu Z, Liu Q, He W, Baxter SW, Yuchi Z, Vasseur L, Gurr GM, Ward CM, Cerda H, Yang G, Peng L, Jin Y, Xie M, Cai L, Douglas CJ, Isman MB, Goettel MS, Song Q, Fan Q, Wang-Pruski G, Lees DC, Yue Z, Bai J, Liu T, Lin L, Zheng Y, Zeng Z, Lin S, Wang Y, Zhao Q, Xia X, Chen W, Chen L, Zou M, Liao J, Gao Q, Fang X, Yin Y, Yang H, Wang J, Han L, Lin Y, Lu Y, Zhuang M. You M, et al. Among authors: goettel ms. Nat Commun. 2020 May 8;11(1):2321. doi: 10.1038/s41467-020-16178-9. Nat Commun. 2020. PMID: 32385305 Free PMC article.
Comparative studies on the effects of sodium phenobarbital and two other constitutive androstane receptor (CAR) activators on induction of cytochrome P450 enzymes and replicative DNA synthesis in cultured hepatocytes from wild type and CAR knockout rats.
Goettel M, Fegert I, Honarvar N, Vardy A, Haines C, Chatham LR, Lake BG. Goettel M, et al. Toxicology. 2020 Mar 30;433-434:152394. doi: 10.1016/j.tox.2020.152394. Epub 2020 Feb 3. Toxicology. 2020. PMID: 32027962
40 results