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A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.
Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A. Palermo A, et al. Among authors: graeber tg. Commun Biol. 2023 Nov 3;6(1):1115. doi: 10.1038/s42003-023-05478-7. Commun Biol. 2023. PMID: 37923961 Free PMC article.
JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma.
Titz B, Lomova A, Le A, Hugo W, Kong X, Ten Hoeve J, Friedman M, Shi H, Moriceau G, Song C, Hong A, Atefi M, Li R, Komisopoulou E, Ribas A, Lo RS, Graeber TG. Titz B, et al. Among authors: graeber tg. Cell Discov. 2016 Sep 6;2:16028. doi: 10.1038/celldisc.2016.28. eCollection 2016. Cell Discov. 2016. PMID: 27648299 Free PMC article.
Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures.
Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, Palaskas N, Wu H, Müschen M, Multani AS, Port E, Larson SM, Schultz N, Braas D, Christofk HR, Mellinghoff IK, Graeber TG. Graham NA, et al. Among authors: graeber tg. Mol Syst Biol. 2017 Feb 15;13(2):914. doi: 10.15252/msb.20167159. Mol Syst Biol. 2017. PMID: 28202506 Free PMC article.
Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia.
Gang EJ, Kim HN, Hsieh YT, Ruan Y, Ogana HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. Gang EJ, et al. Among authors: graeber tg. Blood. 2020 Jul 9;136(2):210-223. doi: 10.1182/blood.2019001417. Blood. 2020. PMID: 32219444 Free PMC article.
Defining the ATPome reveals cross-optimization of metabolic pathways.
Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. Bennett NK, et al. Among authors: graeber tg. Nat Commun. 2020 Aug 28;11(1):4319. doi: 10.1038/s41467-020-18084-6. Nat Commun. 2020. PMID: 32859923 Free PMC article.
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.
Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A. Li S, et al. Among authors: graeber tg. J Clin Invest. 2022 Jan 18;132(2):e149711. doi: 10.1172/JCI149711. J Clin Invest. 2022. PMID: 34813507 Free PMC article.
Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.
Song K, Minami JK, Huang A, Dehkordi SR, Lomeli SH, Luebeck J, Goodman MH, Moriceau G, Krijgsman O, Dharanipragada P, Ridgley T, Crosson WP, Salazar J, Pazol E, Karin G, Jayaraman R, Balanis NG, Alhani S, Sheu K, Ten Hoeve J, Palermo A, Motika SE, Senaratne TN, Paraiso KH, Hergenrother PJ, Rao PN, Multani AS, Peeper DS, Bafna V, Lo RS, Graeber TG. Song K, et al. Among authors: graeber tg. Cancer Discov. 2022 Apr 1;12(4):1046-1069. doi: 10.1158/2159-8290.CD-20-0936. Cancer Discov. 2022. PMID: 34930786 Free PMC article.
136 results