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Discovery of Trace Amine Associated Receptor 1 (TAAR1) Agonist 2-(5-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4H-1,2,4-triazol-3-yl)ethan-1-amine (LK00764) for the Treatment of Psychotic Disorders.
Krasavin M, Lukin A, Sukhanov I, Gerasimov AS, Kuvarzin S, Efimova EV, Dorofeikova M, Nichugovskaya A, Matveev A, Onokhin K, Zakharov K, Gureev M, Gainetdinov RR. Krasavin M, et al. Among authors: gainetdinov rr. Biomolecules. 2022 Nov 7;12(11):1650. doi: 10.3390/biom12111650. Biomolecules. 2022. PMID: 36359001 Free PMC article.
Structure-Based Discovery of Mouse Trace Amine-Associated Receptor 5 Antagonists.
Nicoli A, Weber V, Bon C, Steuer A, Gustincich S, Gainetdinov RR, Lang R, Espinoza S, Di Pizio A. Nicoli A, et al. Among authors: gainetdinov rr. J Chem Inf Model. 2023 Nov 13;63(21):6667-6680. doi: 10.1021/acs.jcim.3c00755. Epub 2023 Oct 17. J Chem Inf Model. 2023. PMID: 37847527 Free PMC article.
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling.
Grossi G, Scarano N, Musumeci F, Tonelli M, Kanov E, Carbone A, Fossa P, Gainetdinov RR, Cichero E, Schenone S. Grossi G, et al. Among authors: gainetdinov rr. Molecules. 2024 Apr 11;29(8):1739. doi: 10.3390/molecules29081739. Molecules. 2024. PMID: 38675561 Free PMC article.
Trace Amine-Associated Receptors' Role in Immune System Functions.
Moiseenko VI, Apryatina VA, Gainetdinov RR, Apryatin SA. Moiseenko VI, et al. Among authors: gainetdinov rr. Biomedicines. 2024 Apr 18;12(4):893. doi: 10.3390/biomedicines12040893. Biomedicines. 2024. PMID: 38672247 Free PMC article. Review.
302 results