Espinoza S - Search Results

1

Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays.

Cichero E, Francesconi V, Casini B, Casale M, Kanov E, Gerasimov AS, Sukhanov I, Savchenko A, Espinoza S, Gainetdinov RR, Tonelli M. Cichero E, et al. Among authors: espinoza s. Pharmaceuticals (Basel). 2023 Nov 20;16(11):1632. doi: 10.3390/ph16111632. Pharmaceuticals (Basel). 2023. PMID: 38004497 Free PMC article.

2

TAAR1-dependent effects of apomorphine in mice.

Sukhanov I, Espinoza S, Yakovlev DS, Hoener MC, Sotnikova TD, Gainetdinov RR. Sukhanov I, et al. Among authors: espinoza s. Int J Neuropsychopharmacol. 2014 Oct;17(10):1683-93. doi: 10.1017/S1461145714000509. Epub 2014 Jun 13. Int J Neuropsychopharmacol. 2014. PMID: 24925023 Free article.

3

Postsynaptic D2 dopamine receptor supersensitivity in the striatum of mice lacking TAAR1.

Espinoza S, Ghisi V, Emanuele M, Leo D, Sukhanov I, Sotnikova TD, Chieregatti E, Gainetdinov RR. Espinoza S, et al. Neuropharmacology. 2015 Jun;93:308-13. doi: 10.1016/j.neuropharm.2015.02.010. Epub 2015 Feb 24. Neuropharmacology. 2015. PMID: 25721394

4

In-vivo pharmacology of Trace-Amine Associated Receptor 1.

Lam VM, Espinoza S, Gerasimov AS, Gainetdinov RR, Salahpour A. Lam VM, et al. Among authors: espinoza s. Eur J Pharmacol. 2015 Sep 15;763(Pt B):136-42. doi: 10.1016/j.ejphar.2015.06.026. Epub 2015 Jun 17. Eur J Pharmacol. 2015. PMID: 26093041 Review.

5

Increased context-dependent conditioning to amphetamine in mice lacking TAAR1.

Sukhanov I, Caffino L, Efimova EV, Espinoza S, Sotnikova TD, Cervo L, Fumagalli F, Gainetdinov RR. Sukhanov I, et al. Among authors: espinoza s. Pharmacol Res. 2016 Jan;103:206-14. doi: 10.1016/j.phrs.2015.11.002. Epub 2015 Dec 2. Pharmacol Res. 2016. PMID: 26640076

6

Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.

Tonelli M, Espinoza S, Gainetdinov RR, Cichero E. Tonelli M, et al. Among authors: espinoza s. Eur J Med Chem. 2017 Feb 15;127:781-792. doi: 10.1016/j.ejmech.2016.10.058. Epub 2016 Oct 27. Eur J Med Chem. 2017. PMID: 27823885

7

Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.

Guariento S, Tonelli M, Espinoza S, Gerasimov AS, Gainetdinov RR, Cichero E. Guariento S, et al. Among authors: espinoza s. Eur J Med Chem. 2018 Feb 25;146:171-184. doi: 10.1016/j.ejmech.2018.01.059. Epub 2018 Feb 4. Eur J Med Chem. 2018. PMID: 29407948

8

Trace amine-associated receptor 1: a multimodal therapeutic target for neuropsychiatric diseases.

Schwartz MD, Canales JJ, Zucchi R, Espinoza S, Sukhanov I, Gainetdinov RR. Schwartz MD, et al. Among authors: espinoza s. Expert Opin Ther Targets. 2018 Jun;22(6):513-526. doi: 10.1080/14728222.2018.1480723. Epub 2018 Jun 5. Expert Opin Ther Targets. 2018. PMID: 29798691 Review.

9

Biochemical and Functional Characterization of the Trace Amine-Associated Receptor 1 (TAAR1) Agonist RO5263397.

Espinoza S, Leo D, Sotnikova TD, Shahid M, Kääriäinen TM, Gainetdinov RR. Espinoza S, et al. Front Pharmacol. 2018 Jun 21;9:645. doi: 10.3389/fphar.2018.00645. eCollection 2018. Front Pharmacol. 2018. PMID: 29977204 Free PMC article.

10

Behavioral Effects of a Potential Novel TAAR1 Antagonist.

Lam VM, Mielnik CA, Baimel C, Beerepoot P, Espinoza S, Sukhanov I, Horsfall W, Gainetdinov RR, Borgland SL, Ramsey AJ, Salahpour A. Lam VM, et al. Among authors: espinoza s. Front Pharmacol. 2018 Sep 4;9:953. doi: 10.3389/fphar.2018.00953. eCollection 2018. Front Pharmacol. 2018. PMID: 30233365 Free PMC article.

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