The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm.
Hamdorf M, Imhof T, Bailey-Elkin B, Betz J, Theobald SJ, Simonis A, Di Cristanziano V, Gieselmann L, Dewald F, Lehmann C, Augustin M, Klein F, Alcazar MAA, Rongisch R, Fabri M, Rybniker J, Goebel H, Stetefeld J, Brachvogel B, Cursiefen C, Koch M, Bock F.
Hamdorf M, et al. Among authors: alcazar maa.
J Mol Cell Biol. 2023 Oct 27:mjad062. doi: 10.1093/jmcb/mjad062. Online ahead of print.
J Mol Cell Biol. 2023.
PMID: 37891014