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Acute expression of human APOBEC3B in mice results in RNA editing and lethality.
Alonso de la Vega A, Temiz NA, Tasakis R, Somogyi K, Salgueiro L, Zimmer E, Ramos M, Diaz-Jimenez A, Chocarro S, Fernández-Vaquero M, Stefanovska B, Reuveni E, Ben-David U, Stenzinger A, Poth T, Heikenwälder M, Papavasiliou N, Harris RS, Sotillo R. Alonso de la Vega A, et al. Genome Biol. 2023 Nov 24;24(1):267. doi: 10.1186/s13059-023-03115-4. Genome Biol. 2023. PMID: 38001542 Free PMC article.
Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases.
Durfee C, Temiz NA, Levin-Klein R, Argyris PP, Alsøe L, Carracedo S, Alonso de la Vega A, Proehl J, Holzhauer AM, Seeman ZJ, Liu X, Lin YT, Vogel RI, Sotillo R, Nilsen H, Harris RS. Durfee C, et al. Among authors: alonso de la vega a. Cell Rep Med. 2023 Oct 17;4(10):101211. doi: 10.1016/j.xcrm.2023.101211. Epub 2023 Oct 4. Cell Rep Med. 2023. PMID: 37797615 Free PMC article.