Cai Z - Search Results

1

Necroptosis inhibitors: mechanisms of action and therapeutic potential.

Zhou Y, Cai Z, Zhai Y, Yu J, He Q, He Y, Jitkaew S, Cai Z. Zhou Y, et al. Among authors: cai z. Apoptosis. 2024 Feb;29(1-2):22-44. doi: 10.1007/s10495-023-01905-6. Epub 2023 Nov 24. Apoptosis. 2024. PMID: 38001341 Review.

2

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.

Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG. Zhao J, et al. Among authors: cai z. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5322-7. doi: 10.1073/pnas.1200012109. Epub 2012 Mar 15. Proc Natl Acad Sci U S A. 2012. PMID: 22421439 Free PMC article.

3

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.

Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J, Ward Y, Wu LG, Liu ZG. Cai Z, et al. Nat Cell Biol. 2014 Jan;16(1):55-65. doi: 10.1038/ncb2883. Epub 2013 Dec 8. Nat Cell Biol. 2014. PMID: 24316671 Free PMC article.

4

The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.

Qin X, Hu L, Shi SN, Chen X, Zhuang C, Zhang W, Jitkaew S, Pang X, Yu J, Tan YX, Wang HY, Cai Z. Qin X, et al. Among authors: cai z. Biochem Pharmacol. 2020 Jul;177:113947. doi: 10.1016/j.bcp.2020.113947. Epub 2020 Apr 2. Biochem Pharmacol. 2020. PMID: 32247850

5

Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma.

Lomphithak T, Akara-Amornthum P, Murakami K, Hashimoto M, Usubuchi H, Iwabuchi E, Unno M, Cai Z, Sasano H, Jitkaew S. Lomphithak T, et al. Among authors: cai z. Sci Rep. 2021 Jun 3;11(1):11743. doi: 10.1038/s41598-021-89977-9. Sci Rep. 2021. PMID: 34083572 Free PMC article.

6

Targeting Necroptosis as a Promising Therapy for Alzheimer's Disease.

Zhao W, Liu Y, Xu L, He Y, Cai Z, Yu J, Zhang W, Xing C, Zhuang C, Qu Z. Zhao W, et al. Among authors: cai z. ACS Chem Neurosci. 2022 Jun 15;13(12):1697-1713. doi: 10.1021/acschemneuro.2c00172. Epub 2022 May 23. ACS Chem Neurosci. 2022. PMID: 35607807 Review.

7

The regulation of necroptosis by ubiquitylation.

Chen Y, Ren W, Wang Q, He Y, Ma D, Cai Z. Chen Y, et al. Among authors: cai z. Apoptosis. 2022 Oct;27(9-10):668-684. doi: 10.1007/s10495-022-01755-8. Epub 2022 Aug 8. Apoptosis. 2022. PMID: 35939135 Review.

8

Identification of a marine-derived sesquiterpenoid, Compound-8, that inhibits tumour necrosis factor-induced cell death by blocking complex II assembly.

He Y, Yang T, Li J, Li K, Zhuang C, Zhang M, Li R, Zhao Y, Song Q, Jiang M, Mao S, Song XG, Guo Y, Li X, Tan F, Jitkaew S, Zhang W, Cai Z. He Y, et al. Among authors: cai z. Br J Pharmacol. 2024 Mar 31. doi: 10.1111/bph.16364. Online ahead of print. Br J Pharmacol. 2024. PMID: 38555910

9

Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration.

Cai Z, Zhang A, Choksi S, Li W, Li T, Zhang XM, Liu ZG. Cai Z, et al. Cell Res. 2016 Aug;26(8):886-900. doi: 10.1038/cr.2016.87. Epub 2016 Jul 22. Cell Res. 2016. PMID: 27444869 Free PMC article.

10

The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis.

Rui C, Shi SN, Ren W, Qin X, Zhuang C, Chen X, Chen G, Yu J, Wang HY, Cai Z. Rui C, et al. Among authors: cai z. Biochem Pharmacol. 2021 Jun;188:114542. doi: 10.1016/j.bcp.2021.114542. Epub 2021 Apr 2. Biochem Pharmacol. 2021. PMID: 33819469

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