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Phase I and II randomized clinical trial of an oral therapeutic vaccine targeting human papillomavirus for treatment of cervical intraepithelial neoplasia 2 and 3.
Kawana K, Kobayashi O, Ikeda Y, Yahata H, Iwata T, Satoh T, Akiyama A, Maeda D, Hori-Hirose Y, Uemura Y, Nakayama-Hosoya K, Katoh K, Katoh Y, Nakajima T, Taguchi A, Komatsu A, Asai-Sato M, Tomita N, Kato K, Aoki D, Igimi S, Kawana-Tachikawa A, Schust DJ. Kawana K, et al. Among authors: taguchi a. JNCI Cancer Spectr. 2023 Oct 31;7(6):pkad101. doi: 10.1093/jncics/pkad101. JNCI Cancer Spectr. 2023. PMID: 38001029 Free PMC article. Clinical Trial.
The prevalence of cervical regulatory T cells in HPV-related cervical intraepithelial neoplasia (CIN) correlates inversely with spontaneous regression of CIN.
Kojima S, Kawana K, Tomio K, Yamashita A, Taguchi A, Miura S, Adachi K, Nagamatsu T, Nagasaka K, Matsumoto Y, Arimoto T, Oda K, Wada-Hiraike O, Yano T, Taketani Y, Fujii T, Schust DJ, Kozuma S. Kojima S, et al. Among authors: taguchi a. Am J Reprod Immunol. 2013 Feb;69(2):134-41. doi: 10.1111/aji.12030. Epub 2012 Oct 11. Am J Reprod Immunol. 2013. PMID: 23057776
Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients.
Kawana K, Adachi K, Kojima S, Taguchi A, Tomio K, Yamashita A, Nishida H, Nagasaka K, Arimoto T, Yokoyama T, Wada-Hiraike O, Oda K, Sewaki T, Osuga Y, Fujii T. Kawana K, et al. Among authors: taguchi a. Vaccine. 2014 Oct 29;32(47):6233-9. doi: 10.1016/j.vaccine.2014.09.020. Epub 2014 Sep 22. Vaccine. 2014. PMID: 25258102 Clinical Trial.
Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer.
Nakamura H, Nagasaka K, Kawana K, Taguchi A, Uehara Y, Yoshida M, Sato M, Nishida H, Fujimoto A, Inoue T, Adachi K, Nagamatsu T, Arimoto T, Oda K, Osuga Y, Fujii T. Nakamura H, et al. Among authors: taguchi a. BMC Cancer. 2016 Nov 17;16(1):897. doi: 10.1186/s12885-016-2929-2. BMC Cancer. 2016. PMID: 27855669 Free PMC article.
Intracellular signaling entropy can be a biomarker for predicting the development of cervical intraepithelial neoplasia.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Ogishima J, Eguchi S, Yamashita A, Tomio K, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Sato M, et al. Among authors: taguchi a. PLoS One. 2017 Apr 28;12(4):e0176353. doi: 10.1371/journal.pone.0176353. eCollection 2017. PLoS One. 2017. PMID: 28453530 Free PMC article.
967 results