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Intraperitoneal administration of carcinoembryonic antigen-directed chimeric antigen receptor T cells is a robust delivery route for effective treatment of peritoneal carcinomatosis from colorectal cancer in pre-clinical study.
Qian S, Chen J, Zhao Y, Zhu X, Dai D, Qin L, Hong J, Xu Y, Yang Z, Li Y, Guijo I, Jiménez-Galanes S, Guadalajara H, García-Arranz M, García-Olmo D, Shen J, Villarejo-Campos P, Qian C. Qian S, et al. Among authors: yang z. Cytotherapy. 2024 Feb;26(2):113-125. doi: 10.1016/j.jcyt.2023.10.007. Epub 2023 Nov 23. Cytotherapy. 2024. PMID: 37999667
KIAA1199 promotes sorafenib tolerance and the metastasis of hepatocellular carcinoma by activating the EGF/EGFR-dependent epithelial-mesenchymal transition program.
Xu Y, Xu H, Li M, Wu H, Guo Y, Chen J, Shan J, Chen X, Shen J, Ma Q, Liu J, Wang M, Zhao W, Hong J, Qi Y, Yao C, Zhang Q, Yang Z, Qian C, Li J. Xu Y, et al. Among authors: yang z. Cancer Lett. 2019 Jul 10;454:78-89. doi: 10.1016/j.canlet.2019.03.049. Epub 2019 Apr 11. Cancer Lett. 2019. PMID: 30980868
Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA+ Metastatic Colorectal Cancers.
Zhang C, Wang Z, Yang Z, Wang M, Li S, Li Y, Zhang R, Xiong Z, Wei Z, Shen J, Luo Y, Zhang Q, Liu L, Qin H, Liu W, Wu F, Chen W, Pan F, Zhang X, Bie P, Liang H, Pecher G, Qian C. Zhang C, et al. Among authors: yang z. Mol Ther. 2017 May 3;25(5):1248-1258. doi: 10.1016/j.ymthe.2017.03.010. Epub 2017 Mar 31. Mol Ther. 2017. PMID: 28366766 Free PMC article. Clinical Trial.
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